Evidence map›Paper›PMID 36222994›Full record

ArticleJournal of autism and developmental disorders2023

The Importance of Language Delays as an Early Indicator of Subsequent ASD Diagnosis in Public Healthcare Settings.

Tanya Nitzan, Judah Koller, Michal Ilan, Michal Faroy, Analya Michaelovski, Idan Menashe, Gal Meiri, Ilan Dinstein

Abstract read
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In one paragraph

Article in Journal of autism and developmental disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Who, when, where, and why: A systematic review of "late diagnosis" in autism.Autism research : official journal of the International Society for Autism Research · 2025
    Pooled it
  2. Article
  3. Article
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  6. Article
  7. Proportion and Profile of Autistic Children Not Acquiring Spoken Language Despite Receiving Evidence-Based Early Interventions.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Investigating the Relationship of Serum CD163, YKL40 and VILIP-1 Levels with Autism Severity and Language-cognitive Development in Preschool Children with Autism.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024
    Article
  14. Do focused interests support word learning? A study with autistic and nonautistic children.Autism research : official journal of the International Society for Autism Research · 2024
    Article
  15. Utility of the Language Use Inventory in Young Children at Elevated Likelihood of Autism.Journal of speech, language, and hearing research : JSLHR · 2024
    Article
  16. The contributions of rare inherited and polygenic risk to ASD in multiplex families.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tanya NitzanPsychology Department, Ben Gurion University, Beer Sheva, Israel. tanyan@post.bgu.ac.il.ORCID http://orcid.org/0000-0003-1263-3262
Judah KollerSeymour Fox School of Education, Hebrew University of Jerusalem, Jerusalem, Israel.
Michal IlanPsychology Department, Ben Gurion University, Beer Sheva, Israel.
Michal FaroyAzrieli National Centre for Autism and Neurodevelopment Research, Ben Gurion University of the Negev, Beer Sheva, Israel.
Analya MichaelovskiAzrieli National Centre for Autism and Neurodevelopment Research, Ben Gurion University of the Negev, Beer Sheva, Israel.
Idan MenasheAzrieli National Centre for Autism and Neurodevelopment Research, Ben Gurion University of the Negev, Beer Sheva, Israel.
Gal MeiriAzrieli National Centre for Autism and Neurodevelopment Research, Ben Gurion University of the Negev, Beer Sheva, Israel.
Ilan DinsteinPsychology Department, Ben Gurion University, Beer Sheva, Israel.

Funding

Azrieli Foundation Azrieli FoundationMinistry of Science, Technology and Space Ministry of Science, Technology and Space
6 · The paper itself

Abstract

Previous studies have reported that ASD children with more severe symptoms are diagnosed earlier. However, previous studies in community settings have mostly relied on retrospective parental reports without the use of quantitative standardized test scores. Here, we evaluated the association of language, cognitive, and ASD severity standardized scores with the age of diagnosis in 1-6-year-old children diagnosed in a public healthcare setting. The results revealed that language scores were the strongest variable associated with the age of diagnosis, explaining ~ 30% of the variability across children. Indeed, all children diagnosed before 30-months of age exhibited moderate-to-severe language delays. These results further substantiate the prominence of language delay as a highly visible symptom associated with earlier ASD diagnosis in community clinical settings.

Indexed as

Autism Spectrum DisorderLanguage Development DisordersChildDelivery of Health CareHumansLanguageRetrospective StudiesAutismAutism spectrum disordersEarly diagnosis, delayed diagnosisLanguage delaySpeech delaySymptom severity

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.