Evidence map›Paper›PMID 36222990›Full record

ArticleJournal of autism and developmental disorders2024

Adaptive Behavior in Young Autistic Children: Associations with Irritability and ADHD Symptoms.

Kimberly L H Carpenter, Naomi O Davis, Marina Spanos, Maura Sabatos-DeVito, Rachel Aiello, Grace T Baranek, Scott N Compton, Helen L Egger, Lauren Franz, Soo-Jeong Kim and 8 more

Open access · greenAbstract read
In one paragraph

Article in Journal of autism and developmental disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Limited Discrepancy Between Cognitive Ability and Daily Living Skills in Autism: A Longitudinal Study From Ages 2-25.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  3. Behavior and Speech Features of Children with ADHD.Healthcare (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Observational
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 2 countries.

Kimberly L H CarpenterDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA. Kimberly.carpenter@duke.edu.ORCID http://orcid.org/0000-0002-3838-798X
Naomi O DavisDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA. naomi.davis@duke.edu.
Marina SpanosDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.
Maura Sabatos-DeVitoDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.
Rachel AielloDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.
Grace T BaranekChan Division of Occupational Science and Occupational Therapy, University of Southern California, Los Angeles, CA, USA.
Scott N ComptonDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.
Helen L EggerLittle Otter Health, LLC, San Francisco, CA, USA.
Lauren FranzDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.
Soo-Jeong KimDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.
Bryan H KingDepartment of Psychiatry and Behavioral Sciences, University of California at San Francisco, San Francisco, CA, USA.
Alexander KolevzonSeaver Autism Center for Research and Treatment, Department of Psychiatry, Icahn School of Medicine at Mount Sinai Hospital, New York, NY, USA.
Christopher J McDougleLurie Center for Autism, Massachusetts General Hospital, Lexington, MA, USA.
Kevin SandersProduct Development Neuroscience, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
Jeremy Veenstra-VanderWeeleDepartment of Psychiatry, Columbia University, New York, NY, USA.
Linmarie SikichDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.
Scott H KollinsDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.
Geraldine DawsonDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.
Duke University · USColumbia University · USMassachusetts General Hospital · USMount Sinai Hospital · USOtter Tail Corporation (United States) · USRoche (Switzerland) · CHUniversity of California, San Francisco · USUniversity of Southern California · USUniversity of Washington · US

Funding

Recruitment and Assessment CoreP50HD093074 · NICHD · DUKE UNIVERSITY · PI Geraldine Dawson · 2017 to 2026
$27.6M
Study of Oxytocin in Autism to Improve Reciprocal Social Behaviors (SOARS-B)U01HD073984 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SIKICH, LINMARIE · 2012 to 2016
$11.8M
National Institute of Child Health and Human Development P50-HD093074National Institute of Child Health and Human Development U01-HD073984NICHD NIH HHS P50 HD093074NICHD NIH HHS U01 HD073984U.S. Department of Defense W81XWH-14-1-0526
6 · The paper itself

Abstract

Attention-deficit/hyperactivity disorder (ADHD) symptoms affect 40-60% of autistic children and have been linked to differences in adaptive behavior. It is unclear whether adaptive behavior in autistic youth is directly impacted by co-occurring ADHD symptoms or by another associated feature of both autism and ADHD, such as increased irritability. The current study examined relationships between irritability, ADHD symptoms, and adaptive behavior in 3- to 7-year-old autistic children. Results suggest that, after adjusting for co-occurring ADHD symptoms, higher levels of irritability are associated with differences in social adaptive behavior specifically. Understanding relationships between irritability, ADHD, and adaptive behavior in autistic children is critical because measures of adaptive behavior, such as the Vineland Scales of Adaptive Functioning, are often used as a proxy for global functioning, as well as for developing intervention plans and measuring outcomes as primary endpoints in clinical trials.

Indexed as

Adaptation, PsychologicalAttention Deficit Disorder with HyperactivityIrritable MoodAutistic DisorderChildChild, PreschoolFemaleHumansMaleSocial BehaviorAdaptive BehaviorAttention-Deficit/Hyperactivity Disorder (ADHD)Autism Spectrum DisorderIrritabilityPreschool Age

Identifiers

PMID36222990
PMCPMC10090229
OpenAlexW4304689794

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.