SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022
The prevalence of depression and anxiety in patients with cancer in Iran: a systematic review and meta-analysis.
Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Global prevalence and determinant factors of pain, depression, and anxiety among cancer patients: an umbrella review of systematic reviews and meta-analyses.BMC psychiatry · 2025Pooled it
- Depression, anxiety and associated factors among cancer patients in Africa; a systematic review and meta-analysis study.BMC psychiatry · 2024Pooled it
- Anxiety and depression among cancer patients in Ethiopia: a systematic review and meta-analysis.Frontiers in psychiatry · 2024Pooled it
- Genetic predispositions for anxiety disorders and major depressive disorder affect current dietary habits in older patients with lifestyle-related diseases.The international journal of neuropsychopharmacology · 2026Article
- Depression, anxiety, and stress in breast cancer patients: prevalence, associated risk factors, and clinical correlates.Scientific reports · 2025Article
- Relationship between spiritual well-being with anxiety and depression among cancer patients.PloS one · 2025Article
- The prevalence of depression and anxiety symptoms and their associated factors among patients with cancer in Qatar: A cross-sectional study.Qatar medical journal · 2025Article
- Article
- Role of emotional control on anxiety and stress among cancer patients.Cancer medicine · 2024Article
- Prospective study of predictors for anxiety, depression, and somatization in a sample of 1807 cancer patients.Scientific reports · 2024Article
- Prevalence of Depression and Anxiety Disorders Among Cancer Patients: An Insight From a Single Institute.Cureus · 2023Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundCancer is one of the most prevalent diseases and is recognized as a global problem that is currently showing a growing trend. Cancer is one of the most stressful circumstances that a person may experience. Given how the mental state of patients with depression and anxiety may have a negative impact on their experience with cancer, this study was conducted with the aim to investigate the prevalence of anxiety and depression in cancer patients in Iran.
methodsThis study was conducted using a systematic review method and based on the guideline Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA 2020). The studies used were searched for via databases, Scopus, Web of Science (WOS), Google Scholar, SID, Magiran, and using keywords related to anxiety, depression, and cancer. After extracting the required data, statistical analysis was performed based on the random model and using the second version of Comprehensive Meta-Analysis Software.
resultsIn a review of 24 studies with a sample size of 3225 people, the overall prevalence of depression in cancer patients in Iran was reported to be 50.1% (95% CI: 40.6-59.6). Additionally, in a review of 15 studies with a sample size of 2009, the overall prevalence of anxiety in cancer patients in Iran was reported to be 40.9% (95% CI: 30.9-51.6). The highest reported prevalence of depression in cancer patients in Iran according to the Beck questionnaire is 64.6 (95% CI: 48.2-78.1). Specifically, the highest prevalence of depression was reported in patients with breast cancer with a prevalence of 66 (95% CI: 50.9-78.4). The highest prevalence of anxiety in patients with cancer in Iran according to the Depression, Anxiety, and Stress Scale was 49.2 (95% CI: 18.9-80.1). Comparatively, the highest prevalence of anxiety in patients with breast cancer was reported to be 53.2 (95% CI: 25.8-78.7).
conclusionThe prevalence of depression and anxiety among cancer patients in Iran, in particular patients with breast cancer, is significantly higher than in other parts of the world. The prevalence found in our study was even higher than the reported number by studies that have examined the disorder globally. Therefore, it is of great urgency for health system policymakers to work to improve the current situation.
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