ArticlePlanta2022
In vivo characterization of key iridoid biosynthesis pathway genes in catnip (Nepeta cataria).
Article in Planta, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Heterogeneity of iridoid biosynthesis in catmints: Molecular background in a phylogenetic context.Journal of integrative plant biology · 2026Article
- Cutting-edge plant natural product pathway elucidation.Current opinion in biotechnology · 2024Review
- Integrating cotyledon-based virus-induced gene silencing with visual marker promises a rapid, highly effective validation of gene functions inFrontiers in plant science · 2024Article
- Transcriptomic and metabolomic analyses reveal the mechanism of color difference between two kinds ofFrontiers in plant science · 2024Article
- Chemical Composition and Anti-Molecules (Basel, Switzerland) · 2023Article
- Functional iridoid synthases from iridoid producing and non-producingFrontiers in plant science · 2023Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
MAIN
conclusionUsing virus-induced gene silencing, we demonstrated that the enzymes GES, ISY, and MLPL are responsible for nepetalactone biosynthesis in Nepeta cataria. Nepetalactone is the main iridoid that is found in the Nepeta genus and is well-known for its psychoactive effect on house cats. Moreover, there is a burgeoning interest into the effect of nepetalactone on insects. Although the enzymes for nepetalactone biosynthesis have been biochemically assayed in vitro, validation of the role that these enzymes have in planta has not been demonstrated. Virus-induced gene silencing (VIGS) is a silencing method that relies on transient transformation and is an approach that has been particularly successful when applied to a variety of non-model plants. Here, we use a recently designed visual-marker dependent VIGS system to demonstrate that the nepetalactone biosynthetic enzymes GES, ISY, and MLPL impact nepetalactone biosynthesis in Nepeta cataria.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.