Evidence map›Paper›PMID 36222834›Full record

ArticleMolecular biology of the cell2022

Dishevelled controls bulk cadherin dynamics and the stability of individual cadherin clusters during convergent extension.

Robert J Huebner, John B Wallingford

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular biology of the cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Oncology Clinical Trials Targeting Members of the Cadherin Superfamily: A Review.Journal of immunotherapy and precision oncology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Robert J HuebnerDepartment of Molecular Biosciences, University of Texas, Austin, TX 78712.
John B WallingfordDepartment of Molecular Biosciences, University of Texas, Austin, TX 78712.
The University of Texas at Austin · US

Funding

Molecular and cell biological basis of convergent extensionR01HD099191 · NICHD · UNIVERSITY OF TEXAS AT AUSTIN · PI John B Wallingford · 2020 to 2026
$2.7M
Control of collective cell movement by planar cell polarity signalingR01GM104853 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI WALLINGFORD, JOHN B · 2015 to 2018
$1.3M
6 · The paper itself

Abstract

Animals are shaped through the movement of large cellular collectives. Such morphogenetic processes require cadherin-based cell adhesion to maintain tissue cohesion and planar cell polarity to coordinate movement. Despite a vast literature surrounding cadherin-based adhesion and planar cell polarity, it is unclear how these molecular networks interface. Here we investigate the relationship between cadherins and planar cell polarity during gastrulation cell movements in

Indexed as

CadherinsGastrulationAnimalsCell AdhesionMorphogenesisXenopus laevisCadherins

Identifiers

PMID36222834
PMCPMC9727802
OpenAlexW4304758604

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.