Evidence map›Paper›PMID 36222604›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2023

Effect of sedatives or anesthetics on the measurement of resting brain function in common marmosets.

Kanako Muta, Junichi Hata, Naoki Kawaguchi, Yawara Haga, Daisuke Yoshimaru, Kei Hagiya, Takaaki Kaneko, Takako Miyabe-Nishiwaki, Yuji Komaki, Fumiko Seki and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. A Novel Directed Seed-Based Connectivity Analysis Toolbox Applied to Human and Marmoset Resting-State FMRI.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Kanako MutaGraduate School of Human Health Sciences, Tokyo Metropolitan University, Arakawa, Tokyo 116-8551, Japan.
Junichi HataGraduate School of Human Health Sciences, Tokyo Metropolitan University, Arakawa, Tokyo 116-8551, Japan.
Naoki KawaguchiGraduate School of Human Health Sciences, Tokyo Metropolitan University, Arakawa, Tokyo 116-8551, Japan.
Yawara HagaGraduate School of Human Health Sciences, Tokyo Metropolitan University, Arakawa, Tokyo 116-8551, Japan.
Daisuke YoshimaruDivision of Regenerative Medicine, The Jikei University School of Medicine, Minato, Tokyo 105-8461, Japan.
Kei HagiyaLaboratory for Marmoset Neural Architecture, Center for Brain Science, RIKEN, Wako, Saitama 351-0198, Japan.
Takaaki KanekoLaboratory for Marmoset Neural Architecture, Center for Brain Science, RIKEN, Wako, Saitama 351-0198, Japan.
Takako Miyabe-NishiwakiCenter for Model Human Evolution Research, Primate Research Institute, Kyoto University, Inuyama, Aichi 484-8506, Japan.
Yuji KomakiDepartment of Physiology, Keio University School of Medicine, Shinjuku, Tokyo 160-8582, Japan.
Fumiko SekiDepartment of Physiology, Keio University School of Medicine, Shinjuku, Tokyo 160-8582, Japan.
Hirotaka James OkanoDivision of Regenerative Medicine, The Jikei University School of Medicine, Minato, Tokyo 105-8461, Japan.
Hideyuki OkanoLaboratory for Marmoset Neural Architecture, Center for Brain Science, RIKEN, Wako, Saitama 351-0198, Japan.
RIKEN Center for Brain Science · JPCentral Institute for Experimental Animals · JPJikei University School of Medicine · JPTokyo Metropolitan University · JPAichi Human Service Center · JPInuyama Chuo Hospital · JPKeio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Common marmosets are promising laboratory animals for the study of higher brain functions. Although there are many opportunities to use sedatives and anesthetics in resting brain function measurements in marmosets, their effects on the resting-state network remain unclear. In this study, the effects of sedatives or anesthetics such as midazolam, dexmedetomidine, co-administration of isoflurane and dexmedetomidine, propofol, alfaxalone, isoflurane, and sevoflurane on the resting brain function in common marmosets were evaluated using independent component analysis, dual regression analysis, and graph-theoretic analysis; and the sedatives or anesthetics suitable for the evaluation of resting brain function were investigated. The results show that network preservation tendency under light sedative with midazolam and dexmedetomidine is similar regardless of the type of target receptor. Moreover, alfaxalone, isoflurane, and sevoflurane have similar effects on resting state brain function, but only propofol exhibits different tendencies, as resting brain function is more preserved than it is following the administration of the other anesthetics. Co-administration of isoflurane and dexmedetomidine shows middle effect between sedatives and anesthetics.

Indexed as

AnestheticsDexmedetomidineIsofluranePropofolAnimalsBrainCallithrixHypnotics and SedativesMidazolamSevofluraneAnestheticsDexmedetomidineHypnotics and SedativesIsofluraneMidazolamPropofolSevofluraneanesthetic effectscommon marmosetresting-state functional magnetic resonance imagingresting state network

Identifiers

PMID36222604
PMCPMC10151911
OpenAlexW4304756783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.