ReviewACS applied materials & interfaces2022
Multifunctional Composite Hydrogels for Bacterial Capture, Growth/Elimination, and Sensing Applications.
Review in ACS applied materials & interfaces, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Polysaccharide-Based Hydrogel Composites With Organic and Inorganic Fillers: Recent Advances in Reinforcement, Functional Properties, and Selected Applications.ChemSusChem · 2026Review
- Chitosan-Based Adhesive Composite Hydrogel to Provide Antibacterial and Anti-Inflammatory Properties for Biomedical Application.Gels (Basel, Switzerland) · 2026Article
- Frontal Polymerization-Enabled Rapid Fabrication of Gelatin-Containing Hydrogels with Good Mechanical and Biological Properties.Gels (Basel, Switzerland) · 2026Article
- Bioinspired and living multiscale composites for regenerative medicine in the treatment of surgical site infections.Journal of nanobiotechnology · 2026Review
- Injectable hydrogels for osteomyelitis treatment induce metabolic reprogramming for protection against reinfection.Nature communications · 2026Article
- Antibacterial hydrogels for skin infected wounds: frontier approaches as antibiotic alternatives therapy.Frontiers in cellular and infection microbiology · 2026Review
- Programmable Hydrogels: Frontiers in Dynamic Closed-Loop Systems, Biomimetic Synergy, and Clinical Translation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Hydrogel Design Based on Bacterial Exopolysaccharides: The Biomedical Promise of Levan.International journal of molecular sciences · 2025Review
- Nanofibrous dressings incorporating a synergistic antibacterial-anti-inflammatory effect for infected wound healing.Materials today. Bio · 2025Article
- Advances in cellulose-based hydrogels: tunable swelling dynamics and their versatile real-time applications.RSC advances · 2025Review
- The landscape of biofilm models for phage therapy: mimicking biofilms in diabetic foot ulcers using 3D models.Frontiers in microbiology · 2025Review
- Sweat, tears, and beyond: advanced wearable sensors for personalized health and athletic performance.Frontiers in bioengineering and biotechnology · 2025Review
- Hydrogels and Their Functionalization-Analysis of the Possibility of Their Application in Post-Fire Water Treatment Processes.Materials (Basel, Switzerland) · 2024Review
- Multi-Functional Biomaterial for the Treatment and Prevention of Central Line-Associated Bloodstream Infections.Advanced materials (Deerfield Beach, Fla.) · 2024Article
- Cutting-Edge Hydrogel Technologies in Tissue Engineering and Biosensing: An Updated Review.Materials (Basel, Switzerland) · 2024Review
- Review
- Harnessing the potential of hydrogels for advanced therapeutic applications: current achievements and future directions.Signal transduction and targeted therapy · 2024Review
- Molybdesum selenide-based platelet-rich plasma containing carboxymethyl chitosan/polyvinyl pyrrolidone composite antioxidant hydrogels dressing promotes the wound healing.Journal of nanobiotechnology · 2024Article
- Assessing electrogenetic activation via a network model of biological signal propagation.Frontiers in systems biology · 2024Article
- Development of phage-containing hydrogel for treating Enterococcus faecalis-infected wounds.PloS one · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hydrogels are cross-linked networks of hydrophilic polymer chains with a three-dimensional structure. Owing to their unique features, the application of hydrogels for bacterial/antibacterial studies and bacterial infection management has grown in importance in recent years. This trend is likely to continue due to the rise in bacterial infections and antimicrobial resistance. By exploiting their physicochemical characteristics and inherent nature, hydrogels have been developed to achieve bacterial capture and detection, bacterial growth or elimination, antibiotic delivery, or bacterial sensing. Traditionally, the development of hydrogels for bacterial/antibacterial studies has focused on achieving a single function such as antibiotic delivery, antibacterial activity, bacterial growth, or bacterial detection. However, recent studies demonstrate the fabrication of multifunctional hydrogels, where a single hydrogel is capable of performing more than one bacterial/antibacterial function, or composite hydrogels consisting of a number of single functionalized hydrogels, which exhibit bacterial/antibacterial function synergistically. In this review, we first highlight the hydrogel features critical for bacterial studies and infection management. Then, we specifically address unique hydrogel properties, their surface/network functionalization, and their mode of action for bacterial capture, adhesion/growth, antibacterial activity, and bacterial sensing, respectively. Finally, we provide insights into different strategies for developing multifunctional hydrogels and how such systems can help tackle, manage, and understand bacterial infections and antimicrobial resistance. We also note that the strategies highlighted in this review can be adapted to other cell types and are therefore likely to find applications beyond the field of microbiology.
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