Evidence map›Paper›PMID 36222503›Full record

ArticleeLife2022

Tumor elimination by clustered microRNAs miR-306 and miR-79 via noncanonical activation of JNK signaling.

Zhaowei Wang, Xiaoling Xia, Jiaqi Li, Tatsushi Igaki

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Zhaowei WangState Key Laboratory of Biocontrol, School of Ecology, Sun Yat-sen University, Shenzhen, China.ORCID 0000-0003-4491-8502
Xiaoling XiaLaboratory of Genetics, Graduate School of Biostudies, Kyoto University, Yoshida-Konoe-cho, Kyoto, Japan.
Jiaqi LiLaboratory of Genetics, Graduate School of Biostudies, Kyoto University, Yoshida-Konoe-cho, Kyoto, Japan.
Tatsushi IgakiLaboratory of Genetics, Graduate School of Biostudies, Kyoto University, Yoshida-Konoe-cho, Kyoto, Japan.ORCID 0000-0001-5839-9526
Kyoto University · JPSouth China Normal University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

JNK signaling plays a critical role in both tumor promotion and tumor suppression. Here, we identified clustered microRNAs (miRNAs) miR-306 and miR-79 as novel tumor-suppressor miRNAs that specifically eliminate JNK-activated tumors in

Indexed as

MicroRNAsNeoplasmsAdenosine Diphosphate RiboseGenes, Tumor SuppressorHumansMAP Kinase Signaling SystemAdenosine Diphosphate RiboseMicroRNAscell biologycell deathD. melanogasterJNK signalingmicroRNAtumor suppression

Identifiers

PMID36222503
PMCPMC9612915
OpenAlexW4304692538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.