Evidence map›Paper›PMID 36222321›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2023

The use of subjective cognitive complaints for detecting mild cognitive impairment in older adults across cultural and linguistic groups: A comparison of the Cognitive Function Instrument to the Montreal Cognitive Assessment.

Clara Li, Yue Hong, Xiao Yang, Xiaoyi Zeng, Katja Ocepek-Welikson, Joseph P Eimicke, Jian Kong, Mary Sano, Carolyn Zhu, Judith Neugroschl and 11 more

Open access · greenAbstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 5 institutions in 1 country.

Clara LiDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Alzheimer's Disease Research Center, New York, New York, USA.
Yue HongMass General Brigham, Salem Hospital, Salem, Massachusetts, USA.
Xiao YangDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Alzheimer's Disease Research Center, New York, New York, USA.
Xiaoyi ZengDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Alzheimer's Disease Research Center, New York, New York, USA.
Katja Ocepek-WeliksonColumbia University Stroud Center, New York State Psychiatric Institute, New York, New York, USA.
Joseph P EimickeThe Hebrew Home at Riverdale, Research Division, Riverdale, New York, USA.
Jian KongThe Hebrew Home at Riverdale, Research Division, Riverdale, New York, USA.
Mary SanoDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Alzheimer's Disease Research Center, New York, New York, USA.
Carolyn ZhuDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Alzheimer's Disease Research Center, New York, New York, USA.
Judith NeugroschlDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Alzheimer's Disease Research Center, New York, New York, USA.
Amy AloysiDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Alzheimer's Disease Research Center, New York, New York, USA.
Dongming CaiDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Alzheimer's Disease Research Center, New York, New York, USA.
Jane MartinDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Alzheimer's Disease Research Center, New York, New York, USA.
Maria LoizosDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Alzheimer's Disease Research Center, New York, New York, USA.
Margaret SewellDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Alzheimer's Disease Research Center, New York, New York, USA.
Jimmy AkrivosDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Alzheimer's Disease Research Center, New York, New York, USA.
Kirsten EvansJames J. Peters VA Medical Center, New York, New York, USA.
Faye SheppardDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Alzheimer's Disease Research Center, New York, New York, USA.
Jonathan GreenbergDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Alzheimer's Disease Research Center, New York, New York, USA.
Allison ArdolinoDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Alzheimer's Disease Research Center, New York, New York, USA.
Jeanne A TeresiColumbia University Stroud Center, New York State Psychiatric Institute, New York, New York, USA.
Icahn School of Medicine at Mount Sinai · USHebrew Home · USColumbia University · USJames J. Peters VA Medical Center · USMassachusetts General Hospital · US

Funding

Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
Research Education ComponentP30AG066514 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Margaret Sewell · 2020 to 2026
$31.0M
Residing in the Community with Dementia at the End of Life: Understanding Hospice Use and Residential SettingP30AG028741 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ALBERT L SIU · 2010 to 2026
$21.9M
Research Education CoreP30AG059303 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Jennifer Jaie Manly · 2018 to 2026
$6.0M
Identifying risk factors of Alzheimer's disease and related dementias in older Chinese immigrantsR21AG077649 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI LI, CLARA · 2022 to 2022
$495k
Evaluating Chinese-speaking community-dwelling elders in the United States with the Uniform Data SetR03AG061439 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI LI, CLARA · 2019 to 2020
$297k
NCATS NIH HHS UL1 TR004419NIA NIH HHS L30 AG069159NIA NIH HHS P30 AG028741NIA NIH HHS P30 AG059303NIA NIH HHS P30 AG066514NIA NIH HHS R03 AG061439NIA NIH HHS R21 AG077649
6 · The paper itself

Abstract

introductionThis pilot study aims to explore the psychometric properties of the Cognitive Function Instrument (CFI) as a measure of subjective cognitive complaints (SCC) and its performance in distinguishing mild cognitive impairment (MCI) from normal control (NC) compared to an objective cognitive screen (Montreal Cognitive Assessment [MoCA]).

methodsOne hundred ninety-four community-dwelling non-demented older adults with racial/ethnic diversity were included. Unidimensionality and internal consistency of the CFI were examined using factor analysis, Cronbach's alpha, and McDonald's omega. Logistic regression models and receiver operating characteristic (ROC) analysis were used to examine the performance of CFI.

resultsThe CFI demonstrated adequate internal consistency; however, the fit for a unidimensional model was suboptimal. The CFI distinguished MCI from NC alone or in combination with MoCA. ROC analysis showed comparable performance of the CFI and the MoCA. DISCUSSION: Our findings support the use of CFI as a brief and easy-to-use screen to detect MCI in culturally/linguistically diverse older adults. HIGHLIGHT: What is the key scientific question or problem of central interest of the paper? Subjective cognitive complaints (SCCs) are considered the earliest sign of dementia in older adults. However, it is unclear if SCC are equivalent in different cultures. The Cognitive Function Instrument (CFI) is a 14-item measure of SCC. This study provides pilot data suggesting that CFI is sensitive for detecting mild cognitive impairment in a cohort of older adults with racial/ethnic diversity. Comparing performance, CFI demonstrates comparable sensitivity to the Montreal Cognitive Assessment, an objective cognitive screening test. Overall, SCC may provide a non-invasive, easy-to-use method to flag possible cognitive impairment in both research and clinical settings.

Indexed as

Cognitive DysfunctionAgedCognitionHumansMental Status and Dementia TestsNeuropsychological TestsPilot Projectsdiverse culturemild cognitive impairmentolder adultsracial/ethnic minoritiessubjective cognitive complaints

Identifiers

PMID36222321
PMCPMC10090224
OpenAlexW4304690979

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.