Evidence map›Paper›PMID 36221771›Full record

ArticleJournal of biomedical materials research. Part B, Applied biomaterials2023

Mechanical alterations of electrospun poly(ϵ-caprolactone) in response to convective thermobonding.

Ali Behrangzade, Hannah R Keeney, Katarina M Martinet, William R Wagner, Jonathan P Vande Geest

Abstract read
In one paragraph

Article in Journal of biomedical materials research. Part B, Applied biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ali BehrangzadeDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Hannah R KeeneyDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Katarina M MartinetDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
William R WagnerDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Jonathan P Vande GeestDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Funding

Cardiovascular Bioengineering Training ProgramT32HL076124 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SANJEEV G SHROFF · 2005 to 2026
$7.0M
Preclinical Assessment of a Compliance Matched Biopolymer Vascular Graft - Diversity SupplementR01HL157017 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VANDE GEEST, JONATHAN PIETER · 2022 to 2025
$3.1M
NHLBI NIH HHS R01 HL157017NHLBI NIH HHS T32 HL076124NIH HHS R01HL157017
6 · The paper itself

Abstract

Vascular graft failure has persisted as a major clinical problem. Mechanical, structural, and transport properties of vascular grafts are critical factors that substantially affect their function and thus the outcome of implantation. The manufacturing method, post-processing technique, and material of choice have a significant impact on these properties. The goal of this work is to use thermal treatment to modulate the transport properties of PCL-based vascular engineered constructs. To this end, we electrospun PCL tubular constructs and thermally bonded the electrospun fibers in a convective oven at various temperatures (54, 57, and 60°C) and durations of treatment (15, 30, and 45 s). The effects of fiber thermal bonding (thermobonding) on the transport, mechanical, and structural properties of PCL tubular constructs were characterized. Increasing the temperature and treatment duration enhanced the degree of thermobonding by removing the interconnected void and fusing the fibers. Thermobonding at 57°C and 60°C for longer than 30 s increased the median tangential modulus (E = 126.1 MPa, [IQR = 20.7]), mean suture retention (F = 193.8 g, [SD = 18.5]), and degradation rate while it decreased the median permeability (k

Indexed as

Tissue EngineeringTissue ScaffoldsBlood Vessel ProsthesisPolyesterspolycaprolactonePolyestersconvective thermobondingelectrospinninghydraulic permeabilitymechanical testingpoly(ϵ-caprolactone)

Identifiers

PMID36221771
PMCPMC10600560

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.