Evidence map›Paper›PMID 36221125›Full record

ArticleBMC musculoskeletal disorders2022

A

Omid Sadatpour, Mohammad Taha Ebrahimi, Maryam Akhtari, Nooshin Ahmadzadeh, Mahdi Vojdanian, Ahmadreza Jamshidi, Elham Farhadi, Mahdi Mahmoudi

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Adenosine-mediated immune responses in inflammatory bowel disease.Frontiers in cell and developmental biology · 2024
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Omid SadatpourDepartment of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Taha EbrahimiRheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Maryam AkhtariRheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Nooshin AhmadzadehRheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Mahdi VojdanianRheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Ahmadreza JamshidiRheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Elham FarhadiRheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Farhadie@tums.ac.ir.
Mahdi MahmoudiRheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran. mahmoudim@tums.ac.ir.
Tehran University of Medical Sciences · IR

Funding

Tehran University of Medical Sciences‎ ‎99-3-96-51351‎
6 · The paper itself

Abstract

backgroundAnkylosing spondylitis (AS) is an inflammatory autoimmune disease that mostly affects different joints of the body. Macrophages are the predominant cells that mediate disease progression by secreting several pro-inflammatory mediators. Different receptors are involved in macrophages' function including the adenosine receptors (AR). Our main objective in this study was to assess the effect of applying A

methodsMonocytes were isolated from the whole blood of 28 individuals (AS patients and healthy controls in a 1:1 ratio). Macrophages were differentiated using macrophage colony-stimulating factor (M-CSF), and flow cytometry was performed to confirm surface markers. CGS-21,680 was used to treat cells that had been differentiated. Using SYBR green real-time PCR, relative gene expression was determined.

resultsActivating A

conclusionDue to the disability of A

Indexed as

Spondylitis, AnkylosingBone Morphogenetic ProteinsHumansInflammation MediatorsMacrophage Colony-Stimulating FactorMacrophagesMatrix Metalloproteinase 8Matrix Metalloproteinase 9Purinergic P1 Receptor AgonistsReceptors, Purinergic P1Severity of Illness IndexBone Morphogenetic ProteinsInflammation MediatorsMacrophage Colony-Stimulating FactorMatrix Metalloproteinase 8Matrix Metalloproteinase 9MMP8 protein, humanPurinergic P1 Receptor AgonistsReceptors, Purinergic P1Adenosine A2A receptorAnkylosing spondylitisBone morphogenetic proteinMacrophagesMatrix metalloproteinase

Identifiers

PMID36221125
PMCPMC9555099
OpenAlexW4304589332

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.