Evidence map›Paper›PMID 36221096›Full record

ArticleJournal of biological engineering2022

Quantitative imaging of magnetic nanoparticles in an unshielded environment using a large AC susceptibility array.

Guilherme Soares, Leonardo Pinto, Maik Liebl, Gabriel Biasotti, Andre Prospero, Erick Stoppa, Andris Bakuzis, Oswaldo Baffa, Frank Wiekhorst, José Ricardo Arruda Miranda

Abstract read
In one paragraph

Article in Journal of biological engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Guilherme SoaresPhysikalisch-Technische Bundesanstalt, Abbestraße 2-12, 10587, Berlin, Germany. guilherme.soares@unesp.br.
Leonardo PintoBiosciences Institute of Botucatu, São Paulo State University, Botucatu, São Paulo, 18618-689, Brazil.
Maik LieblPhysikalisch-Technische Bundesanstalt, Abbestraße 2-12, 10587, Berlin, Germany.
Gabriel BiasottiBiosciences Institute of Botucatu, São Paulo State University, Botucatu, São Paulo, 18618-689, Brazil.
Andre ProsperoBiosciences Institute of Botucatu, São Paulo State University, Botucatu, São Paulo, 18618-689, Brazil.
Erick StoppaBiosciences Institute of Botucatu, São Paulo State University, Botucatu, São Paulo, 18618-689, Brazil.
Andris BakuzisInstitute of Physics, Federal University of Goiás, Goiânia, 74690-900, Brazil.
Oswaldo BaffaFaculty of Philosophy, Sciences and Letters at Ribeirão Preto, University of São Paulo, Ribeirão Preto, Sao Paulo, 14040-900, Brazil.
Frank WiekhorstPhysikalisch-Technische Bundesanstalt, Abbestraße 2-12, 10587, Berlin, Germany.
José Ricardo Arruda MirandaBiosciences Institute of Botucatu, São Paulo State University, Botucatu, São Paulo, 18618-689, Brazil.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 311074/2018-9.Conselho Nacional de Pesquisas e Desenvolvimento Tecnológico 304107/2019-0DFG core facility KO5321/3DFG project "quantMRX" Wi4230/4-1EMPIR program co-financed by the Participating States and from the European Union's Horizon 2020 research and innovation program 16NRM04 "MagNaStand"Fundação de Amparo à Pesquisa do Estado de São Paulo 2021/09829-4German Academic Exchange program DAAD in cooperation with Brazilian CAPES- PROBRAL project ID 57446914, 88887.198747/2018-00 & 888 81.198748/2018-01
6 · The paper itself

Abstract

backgroundNon-invasive magnetic imaging techniques are necessary to assist magnetic nanoparticles in biomedical applications, mainly detecting their distribution inside the body. In Alternating Current Biosusceptometry (ACB), the magnetic nanoparticle's magnetization response under an oscillating magnetic field, which is applied through an excitation coil, is detected with a balanced detection coil system.

resultsWe built a Multi-Channel ACB system (MC-ACB) containing nineteen pick-up coils and obtained 2D quantitative images of magnetic nanoparticle distributions by solving an inverse problem. We reconstructed the magnetic nanoparticles spatial distributions in a field of view of 14 × 14 cm

conclusionBesides other interesting features such as sufficient large field of view dimension for mice and rat studies, portability, and the ability to assess the quantitative magnetic nanoparticles distributions in real-time, the MC-ACB system is a promising tool for quantitative imaging of magnetic nanoparticles distributions in real-time, offering an affordable setup for easy access in clinical or laboratory environments.

Indexed as

Alternate current biosusceptometryInverse problemMagnetic nanoparticlesQuantitative imaging

Identifiers

PMID36221096
PMCPMC9552418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.