Evidence map›Paper›PMID 36220943›Full record

ArticleInternational orthopaedics2022

Total joint arthroplasty following solid organ transplants: complications and mid-term outcomes.

Christine J Wu, Adam C Brekke, Zoe W Hinton, Billy I Kim, Sean P Ryan, Michael P Bolognesi, Thorsten M Seyler

Abstract read
PubMed Publisher
In one paragraph

Article in International orthopaedics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Clinical outcomes of solid organ transplant patients after total joint arthroplasty: a propensity-matched analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Christine J WuDepartment of Orthopaedic Surgery, Duke University, DUMC Box 104002, Durham, NC, 27710, USA. christine.j.wu@duke.edu.ORCID http://orcid.org/0000-0002-2464-9205
Adam C BrekkeTexas Hip and Knee Center, 5450 Clearfork Main Street Ste 100, Fort Worth, TX, 76107, USA.
Zoe W HintonDepartment of Orthopaedic Surgery, Duke University, DUMC Box 104002, Durham, NC, 27710, USA.
Billy I KimSchool of Medicine, Duke University, DUMC 3710, Durham, NC, 27710, USA.
Sean P RyanDepartment of Orthopaedic Surgery, Duke University, DUMC Box 104002, Durham, NC, 27710, USA.
Michael P BolognesiDepartment of Orthopaedic Surgery, Duke University, DUMC Box 104002, Durham, NC, 27710, USA.
Thorsten M SeylerDepartment of Orthopaedic Surgery, Duke University, DUMC Box 104002, Durham, NC, 27710, USA.
Duke University · USTexas Institute for Hip & Knee Surgery · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSurvival after solid organ transplant (SOT) is improving, and demand for total joint arthroplasty (TJA) among SOT recipients is rising. Outcomes including revision, periprosthetic joint infection, and survivorship based on SOT type are variable. We sought to compare peri-operative complications, implant survivorship, and mortality for patients undergoing TJA following SOT.

methodsA retrospective review of the institutional database for primary TJA among SOT recipients from 2000 to 2020 was performed. Revisions, conversion TJA, and patients with multiple organ transplants were excluded. Patients were stratified by transplant organ. Transfusions, 90-day readmissions and emergency department (ED) visits, revisions, and mortality were compared using descriptive statistics and Cox proportional hazard ratios.

resultsA total of 119 total hip arthroplasties (THA) and 63 total knee arthroplasties (TKA) in SOT recipients were studied. Most common SOT was renal (39%), then lung (27%), liver (24%), and heart (10%). TKA postoperative transfusion rates varied by organ (p = 0.037; [heart 0%, liver 9.5%, renal 24.0%, lung 50.0%]). Implant survivorship was 95.6% at one year (95% CI 90.3-98.1) and 92.1% at four years (83.9-96.3). Mortality was 2.9% at one year (95% CI 1.1-7.4) and 23.2% at four years (95% CI 16.1-32.3). After adjusting for procedure, duration from transplant to TJA, age, and Elixhauser Index, lung recipients had higher mortality versus heart (RR 4.39 [95% CI 1.64-15.38]; p = 0.002), kidney (7.98 [3.04-24.61]; p < 0.001), and liver (7.98 [3.04-24.61; p < 0.001) patients.

conclusionTJA after SOT yields acceptable peri-operative outcomes and implant survivorship, but mortality risk is substantial, especially among lung transplant recipients.

Indexed as

Arthroplasty, Replacement, HipArthroplasty, Replacement, KneeOrgan TransplantationHumansPostoperative ComplicationsRetrospective StudiesRisk FactorsTransplant RecipientsComplicationsSolid organ transplantTotal hip arthroplastyTotal knee arthroplasty

Identifiers

PMID36220943
OpenAlexW4304588749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.