Evidence map›Paper›PMID 36220827›Full record

ArticleScientific reports2022

Residential trajectories across the life course and their association with cognitive functioning in later life.

Dan Orsholits, Stéphane Cullati, Boris Cheval, Paolo Ghisletta, Michel Oris, Jürgen Maurer, Matthias Studer, Adilson Marques, Priscila Marconcin, Élvio R Gouveia and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Young adult urbanicity, late midlife neighborhood disadvantage, and cognitive functioning in community-dwelling older men.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
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  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dan OrsholitsCentre for the Interdisciplinary Study of Gerontology and Vulnerability, University of Geneva, 1205, Geneva, Switzerland. Dan.Orsholits@unige.ch.
Stéphane CullatiPopulation Health Laboratory, Department of Community Health, University of Fribourg, 1700, Fribourg, Switzerland.
Boris ChevalSwiss Center for Affective Sciences, University of Geneva, 1202, Geneva, Switzerland.
Paolo GhislettaSwiss National Centre of Competence in Research LIVES - Overcoming Vulnerability: Life Course Perspectives, 1015 Lausanne and 1205 Geneva, Switzerland.
Michel OrisCentre for the Interdisciplinary Study of Gerontology and Vulnerability, University of Geneva, 1205, Geneva, Switzerland.
Jürgen MaurerSwiss National Centre of Competence in Research LIVES - Overcoming Vulnerability: Life Course Perspectives, 1015 Lausanne and 1205 Geneva, Switzerland.
Matthias StuderSwiss National Centre of Competence in Research LIVES - Overcoming Vulnerability: Life Course Perspectives, 1015 Lausanne and 1205 Geneva, Switzerland.
Adilson MarquesCIPER, Faculty of Human Kinetics, University of Lisbon, 1495-751, Lisbon, Portugal.
Priscila MarconcinISAMB, University of Lisbon, 1649-028, Lisbon, Portugal.
Élvio R GouveiaCentre for the Interdisciplinary Study of Gerontology and Vulnerability, University of Geneva, 1205, Geneva, Switzerland.
Matthias KliegelCentre for the Interdisciplinary Study of Gerontology and Vulnerability, University of Geneva, 1205, Geneva, Switzerland.
Andreas IhleCentre for the Interdisciplinary Study of Gerontology and Vulnerability, University of Geneva, 1205, Geneva, Switzerland.

Funding

Understanding and Improving Healthcare Decision-Making and Outcomes for People Living with Alzheimer's Disease and Related DementiasP01AG005842 · NIA · NATIONAL BUREAU OF ECONOMIC RESEARCH · PI JOSEPH J DOYLE · 1986 to 2026
$56.5M
DEVELOPING AN ISRAELI VERSION OF THE HRS/SHARE PROJECTR21AG025169 · NIA · HEBREW UNIVERSITY OF JERUSALEM · PI LITWIN, HOWARD · 2004 to 2006
$297k
NIA NIH HHS HHSN271201300071CNIA NIH HHS P01 AG005842NIA NIH HHS R21 AG025169
6 · The paper itself

Abstract

Previous work has found that later life urban-rural differences in cognitive health can be largely explained by indicators of cognitive reserve such as education or occupation. However, previous research concentrated on residence in limited, specific, periods. This study offers a detailed investigation on the association between urban (vs. rural) residence from birth, and cognitive functioning in older age. Using data from the Survey of Health Ageing and Retirement in Europe we created residential trajectories from birth to survey enrolment with a combination of sequence and cluster analysis. Using mixed-effects models, we investigated the association between residential trajectories in early, mid, and later life and three cognitive functioning outcomes: immediate recall, delayed recall, and verbal fluency. In a sample of 38,165 participants, we found that, even after accounting for differences related to education and occupation, rural (vs. urban) residence in early life remained associated with poorer cognitive performance later in life. This suggests that growing up in rural regions leads to a long-term disadvantage in cognitive functioning. Thus, public health policies should consider that urban-rural inequalities in early life may have long-lasting associations with inequalities in cognitive health in old and very old age.

Indexed as

Healthy AgingLife Change EventsCognitionHumansLongitudinal StudiesRetirementRural Population

Identifiers

PMID36220827
PMCPMC9553870

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.