Evidence map›Paper›PMID 36219475›Full record

ArticleMagnetic resonance in medicine2023

Tensor denoising of multidimensional MRI data.

Jonas L Olesen, Andrada Ianus, Leif Østergaard, Noam Shemesh, Sune N Jespersen

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

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  6. Assessment of TMagma (New York, N.Y.) · 2026
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  9. Axon Diameter Mapping From Myelin Water Diffusion MRI.IEEE transactions on medical imaging · 2026
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  19. Robust-tedana: An automated denoising pipeline for multi-echo fMRI data.bioRxiv : the preprint server for biology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jonas L OlesenCenter of Functionally Integrative Neuroscience, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0003-4624-9816
Andrada IanusChampalimaud Research, Champalimaud Foundation, Lisbon, Portugal.ORCID 0000-0001-9893-1724
Leif ØstergaardCenter of Functionally Integrative Neuroscience, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0003-2930-6997
Noam ShemeshChampalimaud Research, Champalimaud Foundation, Lisbon, Portugal.ORCID 0000-0001-6681-5876
Sune N JespersenCenter of Functionally Integrative Neuroscience, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0003-3146-4329

Funding

MRI Toolbox for Rodent Brain Microstructure ImagingR01EB019980 · NIBIB · VANDERBILT UNIVERSITY · PI DOES, MARK D · 2016 to 2019
$1.8M
NIBIB NIH HHS R01 EB019980
6 · The paper itself

Abstract

purposeTo develop a denoising strategy leveraging redundancy in high-dimensional data. THEORY AND

methodsThe SNR fundamentally limits the information accessible by MRI. This limitation has been addressed by a host of denoising techniques, recently including the so-called MPPCA: principal component analysis of the signal followed by automated rank estimation, exploiting the Marchenko-Pastur distribution of noise singular values. Operating on matrices comprised of data patches, this popular approach objectively identifies noise components and, ideally, allows noise to be removed without introducing artifacts such as image blurring, or nonlocal averaging. The MPPCA rank estimation, however, relies on a large number of noise singular values relative to the number of signal components to avoid such ill effects. This condition is unlikely to be met when data patches and therefore matrices are small, for example due to spatially varying noise. Here, we introduce tensor MPPCA (tMPPCA) for the purpose of denoising multidimensional data, such as from multicontrast acquisitions. Rather than combining dimensions in matrices, tMPPCA uses each dimension of the multidimensional data's inherent tensor-structure to better characterize noise, and to recursively estimate signal components.

resultsRelative to matrix-based MPPCA, tMPPCA requires no additional assumptions, and comparing the two in a numerical phantom and a multi-TE diffusion MRI data set, tMPPCA dramatically improves denoising performance. This is particularly true for small data patches, suggesting that tMPPCA can be especially beneficial in such cases.

conclusionsThe MPPCA denoising technique can be extended to high-dimensional data with improved performance for smaller patch sizes.

Indexed as

AlgorithmsMagnetic Resonance ImagingBrainDiffusion Magnetic Resonance ImagingPhantoms, ImagingPrincipal Component AnalysisSignal-To-Noise Ratiodenoisingdiffusionprincipal component analysisrandom matrix theory

Identifiers

PMID36219475
PMCPMC10092037

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.