ArticleJournal of cancer survivorship : research and practice2023
Health-related quality of life 15 years after oesophageal cancer surgery: a prospective nationwide cohort study.
Article in Journal of cancer survivorship : research and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Health-related quality of life in esophageal cancer: a state-of-the-art review of patient-reported outcomes and an evidence and gap map.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2025Pooled it
- Self-care advice for patients after surgery for oesophageal cancer - a mixed-methods systematic review.Journal of cancer survivorship : research and practice · 2025Pooled it
- Bridging symptoms linking postoperative symptom clusters seven days after esophagectomy: A multicenter network analysis of 418 patients with esophageal cancer.Asia-Pacific journal of oncology nursing · 2026Article
- Factors associated with self-care engagement among oesophageal and gastric cancer survivors: a population-based cross-sectional study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Factors associated with anticipatory grief in family caregivers of patients with esophageal cancer: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Investigating Nutrition and Supportive Care Needs in Esophageal and Gastric Cancer Survivors: A Cross-Sectional Survey.Healthcare (Basel, Switzerland) · 2025Article
- The impact of the Covid-19 pandemic on outpatient visits for patients with cancer in Iran: an interrupted time series analysis.Archives of public health = Archives belges de sante publique · 2025Article
- A trial-ready cohort for finding unmet needs and improving quality of life among patients with esophageal cancer: a multicenter prospective cohort study.Frontiers in oncology · 2025Article
- Postoperative complications and health-related quality of life after oesophageal cancer surgery: a national, population-based cohort study.Acta oncologica (Stockholm, Sweden) · 2024Article
- Reasons for fear of cancer recurrence after endoscopic treatment of T1 esophageal adenocarcinoma. A semi-structured interview study.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2024Article
- The Cytotoxic Effect of Ciprofloxacin Laetrile Combination on Esophageal Cancer Cell Line.Asian Pacific journal of cancer prevention : APJCP · 2024Article
- Health-related quality of life among patients with esophageal, gastric, and colorectal cancer at Kenyatta National Hospital.Cancer reports (Hoboken, N.J.) · 2024Article
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe aimed to study oesophageal cancer survivors' health-related quality of life (HRQL) 15 years after surgery and to identify factors related to reduced HRQL.
methodsA nationwide, prospective cohort study enrolling 616 patients who underwent open oesophageal cancer surgery in Sweden between April 2, 2001, and December 21, 2005. HRQL was evaluated by questionnaires 15 years after surgery. HRQL data for the 15-year survivors were individually matched for age, sex and comorbidity by using values from a Swedish background population. Multivariable linear regression models provided mean score differences (MSD) with 95% confidence intervals (CI) for each HRQL scale and item.
resultsAmong the 616 individuals in the original study group, 70 (11%) survived for 15 years and 52 (74%) responded to the questionnaires. Compared with a matched background population, the survivors reported problems in 10 of 25 HRQL aspects. Most of these were related to symptoms of the digestive tract, such as reflux (MSD 26.4, 95%CI: 18.3 to 34.4), dysphagia (MSD 17.7, 95%CI: 10.0 to 25.4) and eating difficulties (MSD 16.4, 95%CI: 11.3 to 21.4). Major postoperative complications after surgery were related to worse HRQL in 11 of 25 aspects.
conclusionsThis study suggests that surgery for oesophageal cancer entails long-term, possibly life-long, symptoms related to the digestive tract. IMPLICATION FOR CANCER SURVIVORS: Comprehensive support from healthcare may be imperative for oesophageal cancer survivors to adapt to and cope with consequences of oesophageal cancer surgery. Prevention, early identification and adequate treatment of postoperative complications may improve patient outcome.
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