Evidence map›Paper›PMID 36218483›Full record

ArticleRheumatology (Oxford, England)2023

Nationwide racial/ethnic disparities in US emergency department visits and hospitalizations for gout.

Chio Yokose, Natalie McCormick, Na Lu, Amit D Joshi, Lesley Jackson, Minna J Kohler, Janeth Yinh, Yuqing Zhang, John Hsu, Nicola Dalbeth and 2 more

Open access · greenAbstract read
In one paragraph

Article in Rheumatology (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Hyperuricaemia and gout in the Pacific.Nature reviews. Rheumatology · 2025
    Review
  5. Article
  6. The Evolving Landscape of Gout in the Female: A Narrative Review.Gout, urate, and crystal deposition disease · 2023
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Chio YokoseDivision of Rheumatology, Department of Medicine, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0001-7557-3303
Natalie McCormickDivision of Rheumatology, Department of Medicine, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0002-4147-8348
Na LuArthritis Research Canada, Vancouver, BC, Canada.
Amit D JoshiChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Lesley JacksonDivision of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Minna J KohlerDivision of Rheumatology, Department of Medicine, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, USA.
Janeth YinhDivision of Rheumatology, Department of Medicine, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, USA.
Yuqing ZhangDivision of Rheumatology, Department of Medicine, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, USA.
John HsuMongan Institute, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Nicola DalbethDepartment of Medicine, University of Auckland, Auckland, New Zealand.
Kenneth G SaagDivision of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Hyon K ChoiDivision of Rheumatology, Department of Medicine, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, USA.
Massachusetts General Hospital · USBrigham and Women's Hospital · USUniversity of Alabama at Birmingham · USHarvard University · USUniversity of Auckland · NZ

Funding

The Effects of Urate Lowering Therapy on Inflammation, Endothelial function, andP50AR060772 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SAAG, KENNETH G · 2012 to 2021
$12.8M
NOVEL METABOLITE AND MICROBIOTA PATHWAYS FOR HYPERURICEMIA AND GOUTR01AR065944 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI CHOI, HYON K · 2013 to 2025
$4.2M
Training Program in Rheumatic and Musculoskeletal Diseases ResearchT32AR069516 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI John D Mountz · 2016 to 2026
$2.6M
Metabolic syndrome, chronic inflammation, and gout: a multi-omics approachR00AR080243 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI Natalie McCormick · 2025 to 2026
$461k
Metabolic syndrome, chronic inflammation, and gout: a multi-omics approachK99AR080243 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI MCCORMICK, NATALIE · 2022 to 2023
$188k
NIAMS NIH HHS K99 AR080243NIAMS NIH HHS P50 AR060772NIAMS NIH HHS R00 AR080243NIAMS NIH HHS R01 AR065944NIAMS NIH HHS T32 AR069516
6 · The paper itself

Abstract

objectivesGout prevalence is reportedly ∼20% higher in US Black adults than Whites, but racial differences in emergency department (ED) visits and hospitalizations for gout are unknown. We evaluated the latest US national utilization datasets according to racial/ethnic groups.

methodsUsing 2019 US National Emergency Department Sample and National Inpatient Sample databases, we compared racial/ethnic differences in annual population rates of ED visits and hospitalizations for gout (primary discharge diagnosis) per 100 000 US adults (using 2019 age- and sex-specific US census data). We also examined rates of ED visits and hospitalizations for gout among all US ED visits/hospitalizations and mean costs for each gout encounter.

resultsCompared with White patients, the per capita age- and sex-adjusted rate ratio (RR) of gout primary ED visits for Black patients was 5.01 (95% CI 4.96, 5.06), for Asian patients 1.29 (1.26, 1.31) and for Hispanic patients 1.12 (1.10, 1.13). RRs for gout primary hospitalizations were 4.07 (95% CI 3.90, 4.24), 1.46 (1.34, 1.58) and 1.06 (0.99, 1.13), respectively. Corresponding RRs among total US hospitalizations were 3.17 (95% CI 2.86, 3.50), 3.23 (2.71, 3.85) and 1.43 (1.21, 1.68) and among total ED visits were 2.66 (95% CI, 2.50, 2.82), 3.28 (2.64, 4.08), and 1.14 (1.05, 1.24), respectively. RRs were largest among Black women. Costs for ED visits and hospitalizations experienced by race/ethnicity showed similar disparities.

conclusionsThese first nationwide data found a substantial excess in both gout primary ED visits and hospitalizations experienced by all underserved racial/ethnic groups, particularly by Black women, revealing an urgent need for improved care to eliminate inequities in gout outcomes.

Indexed as

Emergency Service, HospitalFacilities and Services UtilizationGoutHealthcare DisparitiesHospitalizationAdultAsianBlack or African AmericanEthnicityFemaleHispanic or LatinoHumansMaleUnited StatesWhiteepidemiologygouthealthcare utilizationhealth inequitieshospitalizationsracial disparities

Identifiers

PMID36218483
PMCPMC10234199
OpenAlexW4304481136

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.