Evidence map›Paper›PMID 36218346›Full record

ArticlemSphere2022

Serratia marcescens DUF1471-Containing Protein SrfN Is Needed for Adaptation to Acid and Oxidative Stresses.

Anna A Elistratova, Lilia E Matrosova, Irina V Khilyas, Tatiana V Shirshikova, Iuliia V Danilova, Alexander V Laikov, Yulia D Romanova, Cecilia G Sierra-Bakhshi, Margarita R Sharipova, Lydia M Bogomolnaya

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Copper-induced stress mechanisms inApplied and environmental microbiology · 2025
    Article
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  5. Outbreak ofAdvances in medicine · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Anna A ElistratovaDepartment of Microbiology, Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University, Kazan, Russia.
Lilia E MatrosovaDepartment of Microbiology, Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University, Kazan, Russia.
Irina V KhilyasDepartment of Microbiology, Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University, Kazan, Russia.
Tatiana V ShirshikovaDepartment of Microbiology, Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University, Kazan, Russia.
Iuliia V DanilovaDepartment of Microbiology, Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University, Kazan, Russia.
Alexander V LaikovOpenLab "Omics Technologies," Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University, Kazan, Russia.ORCID 0000-0002-4250-2645
Yulia D RomanovaMedical Research Center Immunculus, Moscow, Russia.
Cecilia G Sierra-BakhshiDepartment of Biomedical Sciences, Joan C. Edwards School of Medicine, Marshall Universitygrid.259676.9, Huntington, West Virginia, USA.
Margarita R SharipovaDepartment of Microbiology, Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University, Kazan, Russia.
Lydia M BogomolnayaDepartment of Biomedical Sciences, Joan C. Edwards School of Medicine, Marshall Universitygrid.259676.9, Huntington, West Virginia, USA.ORCID 0000-0001-7041-1815
Kazan Federal University · RUMarshall University · US

Funding

WV INBRE: The Inhibitor of Growth Family Member 4 (ING4) inhibits L-Type Amino Acid Transporter 1 (LAT1) expression to suppress Breast CancerP20GM103434 · NIGMS · MARSHALL UNIVERSITY · PI Travis Salisbury · 2012 to 2026
$61.1M
HHS | NIH | National Institute of General Medical Sciences (NIGMS) P20GM103434
6 · The paper itself

Abstract

Bacteria can quickly adapt to constantly changing environments through a number of mechanisms, including secretion of secondary metabolites, peptides, and proteins. Serratia marcescens, an emerging pathogen with growing clinical importance due to its intrinsic resistance to several classes of antibiotics, can cause an array of infections in immunocompromised individuals. To better control the spread of S. marcescens infections, it is critical to identify additional targets for bacterial growth inhibition. We found that extracellular metabolites produced by the wild-type organism in response to peroxide exposure had a protective effect on an otherwise-H

Indexed as

Hydrogen PeroxideSerratia marcescensAnimalsAnti-Bacterial AgentsCulture Media, ConditionedHumansOxidative StressAnti-Bacterial AgentsCulture Media, ConditionedHydrogen PeroxideDUF1471-containing proteinoxidative stressSerratia marcescensSrfN

Identifiers

PMID36218346
PMCPMC9769812
OpenAlexW4304191938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.