Evidence map›Paper›PMID 36218255›Full record

ArticleRevista de neurologia2022

[Guillain-Barre syndrome and thrombocytopenia after SARS-CoV-2 vaccination with Moderna. A case report].

C Lázaro, A Llauradó, D Sánchez-Tejerina, A Cabirta, C Carpio, J Sotoca, M Salvadó, N Raguer, J Restrepo, R Juntas

Open access · greenAbstract readCase Reports
In one paragraph

Article in Revista de neurologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

C LázaroHospital Universitari Vall d'Hebron, 08035 Barcelona, España.
A LlauradóHospital Universitari Vall d'Hebron, 08035 Barcelona, España.
D Sánchez-TejerinaHospital Universitari Vall d'Hebron, 08035 Barcelona, España.
A CabirtaHospital Universitari Vall d'Hebron, 08035 Barcelona, España.
C CarpioHospital Universitari Vall d'Hebron, 08035 Barcelona, España.
J SotocaHospital Universitari Vall d'Hebron, 08035 Barcelona, España.
M SalvadóHospital Universitari Vall d'Hebron, 08035 Barcelona, España.
N RaguerHospital Universitari Vall d'Hebron, 08035 Barcelona, España.
J RestrepoHospital Universitari Vall d'Hebron, 08035 Barcelona, España.
R JuntasHospital Universitari Vall d'Hebron, 08035 Barcelona, España.
Vall d'Hebron Hospital Universitari · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe massive vaccination against the SARS-CoV-2 virus has demonstrated to be one of the major measures for the reduction of the morbidity and mortality that this virus causes. However, during the last months the administration of the vaccine has been also associated with some rare, but life-threatening, adverse effects. CASE REPORT: In this article we describe the case of a patient that developed a Guillain-Barre syndrome and an Idiopathic thrombocytopenic purpura nine days after the vaccination with the third dose for the SARS-CoV-2 virus (Moderna). He had received previously two doses of the AstraZeneca vaccine. Moreover, the patient was positive for auto-antibodies anti-SSA/Ro60 and auto-antibodies IgG anti-GM1 and IgG anti-GM3. DISCUSSION: Even though it is not possible to stablish a clear relation of causality between the administration of the vaccine booster for SARS-CoV-2 and the diseases developed by the patient, the association of two concomitant autoimmune processes is remarkable. As well as the positivity for the auto-antibodies anti-SSA/Ro60, which have been described in the bibliography in cases of SARS-CoV-2 infection.

Indexed as

COVID-19COVID-19 VaccinesGuillain-Barre SyndromeThrombocytopeniaHumansImmunoglobulin GMaleSARS-CoV-2VaccinationViral VaccinesCOVID-19 VaccinesImmunoglobulin GViral Vaccines

Identifiers

PMID36218255
PMCPMC10280725
OpenAlexW4304481340

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.