Evidence map›Paper›PMID 36218226›Full record

ArticleLeukemia & lymphoma2023

Perturbation of the gut microbiome and association with outcomes following autologous stem cell transplantation in patients with multiple myeloma.

Christopher D'Angelo, Sailendharan Sudakaran, Fotis Asimakopoulos, Peiman Hematti, Dalia El-Gamal, Nasia Safdar, Natalie Callander

Abstract read
In one paragraph

Article in Leukemia & lymphoma, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. A liberalized diet does not improve caloric intake during neutropenia in patients undergoing hematopoietic stem cell transplants: A prospective randomized controlled trial.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025
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  11. Impact of ExogenousAntibiotics (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Christopher D'AngeloFred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA.
Sailendharan SudakaranMoores Cancer Center, University of California at San Diego, San Diego, CA, USA.
Fotis AsimakopoulosWisconsin Institute for Discovery, University of Wisconsin - Madison, Madison, WI, USA.
Peiman HemattiDepartment of Medicine, University of Wisconsin Carbone Cancer Center Madison, WI, USA.
Dalia El-GamalFred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA.
Nasia SafdarDepartment of Medicine, University of Wisconsin Carbone Cancer Center Madison, WI, USA.
Natalie CallanderDepartment of Medicine, University of Wisconsin Carbone Cancer Center Madison, WI, USA.

Funding

RESEARCH TRAINING IN HEMATOLOGYT32HL007899 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Jane Ellen Churpek · 1998 to 2026
$8.2M
Tumor matrix remodeling in anti-myeloma immunity and immunotherapyR01CA252937 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ASIMAKOPOULOS, FOTIOS · 2020 to 2024
$2.5M
NCI NIH HHS L30 CA242709NCI NIH HHS R01 CA252937NHLBI NIH HHS T32 HL007899
6 · The paper itself

Abstract

The gut microbiome is an important feature of host immunity with associations to hematologic malignancies and cellular therapy. We evaluated the gut microbiome and dietary intake in patients with multiple myeloma undergoing autologous stem cell transplantation. Thirty patients were enrolled, and samples were collected at four timepoints: pre-transplant, engraftment, day +100 (

Indexed as

Gastrointestinal MicrobiomeHematopoietic Stem Cell TransplantationMultiple MyelomaAntineoplastic Combined Chemotherapy ProtocolsDisease-Free SurvivalHumansStem Cell TransplantationTransplantation, AutologousTreatment Outcomeantibioticsautologous stem cell transplantMicrobiomemultiple myelomanutrition

Identifiers

PMID36218226
PMCPMC9905274

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.