Evidence map›Paper›PMID 36218130›Full record

ReviewJournal of applied biomedicine2022

Photodynamic therapy in breast cancer treatment.

Joanna Gustalik, David Aebisher, Dorota Bartusik-Aebisher

Open access · goldAbstract readReview
PubMed Publisher
In one paragraph

Review in Journal of applied biomedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pregnancy after cancer: FIGO Best practice advice.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Guideline
  2. Article
  3. Article
  4. Article
  5. Review
  6. Spiegelmer Aptamers: Innovative Approach in Breast Cancer.Breast cancer : basic and clinical research · 2026
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Application of fluorocarbon nanoparticles ofJournal of nanobiotechnology · 2024
    Article
  15. Photodynamic Therapy and Cardiovascular Diseases.International journal of molecular sciences · 2024
    Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Joanna GustalikDepartment of Pathomorphology, Medical College of The University of Rzeszow, University of Rzeszow, Poland.
David AebisherDepartment of Photomedicine and Physical Chemistry, Medical College of The University of Rzeszow, University of Rzeszow, Rzeszow Poland.
Dorota Bartusik-AebisherDepartment of Biochemistry and General Chemistry, Medical College of The University of Rzeszow, University of Rzeszow, Rzeszow, Poland.
Rzeszów University · PL

Funding

National Center of Science NCN 2017/25/B/ST4/02481National Center of Science NCN OPUS-13
6 · The paper itself

Abstract

Breast cancer is a serious public problem in modern society. Photodynamic therapy (PDT) is increasingly used in modern medicine. Currently, PDT is an innovative method of treating breast cancer. Irreversible damage to neoplastic tissues is associated with the use of physicochemical processes. Generating cytotoxic reactive oxygen species [singlet oxygen (1O2)] is leading to tumor cell death. At the same time, valuable information can be extracted from breast cancer cells. Photogenerated 1O2 is the major factor responsible for cell necrosis during PDT. 1O2 can react rapidly intracellularly with all organic substances. The use of photodynamic therapy on tissues in vitro creates conditions for testing various types of solutions and implementing them in in vivo treatment. This article is a review of recent advances in PDT for treatment of breast cancer. PDT is a novel cancer diagnostic and cancer treatment therapy. Therefore, an understanding of the possibility to generate a toxic form of 1O2 is necessary. The knowledge gained from the basics of PDT in vitro can be useful in biomedical applications in vivo. The current literature mentions PDT in the treatment of cancers located very deep within the human body. Therefore, the development of agents used to deliver 1O2 to the deep cancerous tissue is a new challenge which can have an efficient impact on this discipline. This review covers the literature between 2000-2022.

Indexed as

Breast NeoplasmsPhotochemotherapyFemaleHumansReactive Oxygen SpeciesSinglet OxygenReactive Oxygen SpeciesSinglet OxygenBreast cancer tissuesIntracellularPhotodynamic therapyReactive oxygen speciesTreatment

Identifiers

PMID36218130
OpenAlexW4300979618

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.