Evidence map›Paper›PMID 36218005›Full record

ArticleCancer medicine2023

Losing a child to adolescent cancer: A register-based cohort study of psychotropic medication use in bereaved parents.

Emma Hovén, Lisa Ljungman, Josefin Sveen, Charlotte Skoglund, Gustaf Ljungman, Rickard Ljung, Anna Wikman

Open access · goldFull text read
In one paragraph

Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Emma HovénDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.ORCID 0000-0001-9335-9714
Lisa LjungmanDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.ORCID 0000-0002-4512-8900
Josefin SveenDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Charlotte SkoglundDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Gustaf LjungmanDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Rickard LjungUnit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-0654-4530
Anna WikmanDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Uppsala University · SEKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the short- and long-term risk of psychotropic medication use in parents who lose a child to cancer diagnosed in adolescence.

methodsThis is a Swedish nationwide register-based study including 184 bereaved mothers and 184 bereaved fathers of 184 children diagnosed with cancer in adolescence. Logistic regression analyses, adjusted for sociodemographic characteristics and history of mental health problems, were performed to estimate risk of a prescription of psychotropic medication (anxiolytics, hypnotics/sedatives, antidepressants) in cancer-bereaved parents from 1 year before to 5 years after the child's death, with a general population sample of non-bereaved parents (n = 3291) as referents.

resultsAt the year of the child's death, 28%-36% of mothers and 11%-20% of fathers had a prescription of anxiolytics, hypnotics/sedatives or antidepressants. The corresponding percentages for non-bereaved mothers and fathers were 7%-12% and 4%-7%, respectively. Compared to non-bereaved mothers, bereaved mothers showed higher odds of prescriptions from 1 year before up to four (anxiolytics) and 5 years (hypnotics/sedatives and antidepressants) after the child's death. Bereaved fathers showed higher odds than non-bereaved fathers of prescriptions from 1 year before up to the year of (anxiolytics and hypnotics/sedatives) and 1 year after (antidepressants) the child's death. No differences in odds between bereaved and non-bereaved fathers were found at 2 years after the child's death. Being unmarried, born outside Sweden, and having a history of mental health problems were associated with higher odds of prescribed medications.

conclusionsIndicative of mental health problems of clinical importance, cancer-bereaved parents had a higher prevalence of use of psychotropic medication. A decrease in medication use was evident with time, but still at 5 years after the child's death mothers displayed a higher use while fathers showed no difference to non-bereaved fathers after 2 years.

Indexed as

BereavementDeathParentsPsychotropic DrugsAdolescentAdultAnti-Anxiety AgentsAntidepressive AgentsFemaleHumansHypnotics and SedativesMaleMiddle AgedNeoplasmsSwedenAnti-Anxiety AgentsAntidepressive AgentsHypnotics and SedativesPsychotropic Drugsadolescencebereavementcancerparentspsychotropic medication

Identifiers

PMID36218005
PMCPMC10028064
OpenAlexW4304184035

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read79
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.