Evidence map›Paper›PMID 36217899›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2023

On the Mechanism of the Formal [2+2] Cycloaddition - Retro-electrocyclization (CA-RE) Reaction.

Jonathan Kirschner Solberg Hansen, Christian G Tortzen, Preben Graae Sørensen, Mogens Brøndsted Nielsen

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jonathan Kirschner Solberg HansenDepartment of Chemistry, University of Copenhagen, Universitetsparken 5, 2100, Copenhagen, Denmark.
Christian G TortzenDepartment of Chemistry, University of Copenhagen, Universitetsparken 5, 2100, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-3672-6423
Preben Graae SørensenDepartment of Chemistry, University of Copenhagen, Universitetsparken 5, 2100, Copenhagen, Denmark.
Mogens Brøndsted NielsenDepartment of Chemistry, University of Copenhagen, Universitetsparken 5, 2100, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-8377-0788

Funding

Carlsbergfondet CF17-0050Novo Nordisk Fonden NNF20OC0061574
6 · The paper itself

Abstract

The [2+2] cycloaddition - retro-electrocyclization (CA-RE) reaction is a "click-like" protocol for facile synthesis of donor-acceptor chromophores from an alkyne and tetracyanoethylene. Herein we shed light on the mechanism of this reaction by detailed kinetics studies using

Indexed as

AlkynesCyclizationCycloaddition ReactionMagnetic Resonance SpectroscopyAlkynesautocatalysiscycloadditionkineticsNMR spectroscopyretro-electrocyclization

Identifiers

PMID36217899
PMCPMC10099493

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.