Evidence map›Paper›PMID 36217719›Full record

ArticleThe Journal of physiology2022

The vital role of arcuate nociceptin/orphanin FQ neurones in mounting an oestradiol-dependent adaptive response to negative energy balance via inhibition of nearby proopiomelanocortin neurones.

Sarah Sayers, Nikki Le, Jennifer Hernandez, Veronica Mata-Pacheco, Edward J Wagner

Open access · hybridAbstract read
In one paragraph

Article in The Journal of physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sarah SayersGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, USA.
Nikki LeGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, USA.
Jennifer HernandezGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, USA.
Veronica Mata-PachecoGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, USA.
Edward J WagnerCollege of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA, USA.ORCID 0000-0002-9630-5217
Western University of Health Sciences · US

Funding

Sex Differences in the Cannabioid Regulation of Energy HomeostasisR15DA024314 · NIDA · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI WAGNER, EDWARD J · 2008 to 2020
$1.5M
NIH HHS DA024314
6 · The paper itself

Abstract

We tested the hypothesis that N/OFQ neurones in the arcuate nucleus (N/OFQ

Indexed as

EstradiolPro-OpiomelanocortinAnimalsEnergy MetabolismFemaleHyperphagiaMaleMiceNociceptinOpioid PeptidesEstradiolNociceptinOpioid PeptidesPro-Opiomelanocortinenergy balancefastingnociceptin/orphanin FQoestradiolproopiomelanocortinsex differences

Identifiers

PMID36217719
PMCPMC9828807
OpenAlexW4304172455

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.