Evidence map›Paper›PMID 36217429›Full record

ArticlePhysics and imaging in radiation oncology2022

Same-day consultation, simulation and lung Stereotactic Ablative Radiotherapy delivery on a Magnetic Resonance-linac.

Miguel A Palacios, Sonja Verheijen, Famke L Schneiders, Omar Bohoudi, Berend J Slotman, Frank J Lagerwaard, Suresh Senan

Open access · goldAbstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Miguel A PalaciosAmsterdam UMC, Vrije Universiteit Medical Centre, Dept. of Radiation Oncology, de Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.
Sonja VerheijenAmsterdam UMC, Vrije Universiteit Medical Centre, Dept. of Radiation Oncology, de Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.
Famke L SchneidersAmsterdam UMC, Vrije Universiteit Medical Centre, Dept. of Radiation Oncology, de Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.
Omar BohoudiAmsterdam UMC, Vrije Universiteit Medical Centre, Dept. of Radiation Oncology, de Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.
Berend J SlotmanAmsterdam UMC, Vrije Universiteit Medical Centre, Dept. of Radiation Oncology, de Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.
Frank J LagerwaardAmsterdam UMC, Vrije Universiteit Medical Centre, Dept. of Radiation Oncology, de Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.
Suresh SenanAmsterdam UMC, Vrije Universiteit Medical Centre, Dept. of Radiation Oncology, de Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.
Vrije Universiteit Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Purpose: Magnetic resonance-guided radiotherapy (MRgRT) with real-time intra-fraction tumor motion monitoring allows for high precision Stereotactic Ablative Radiotherapy (SABR). This study aimed to investigate the clinical feasibility, patient satisfaction and delivery accuracy of single-fraction MR-guided SABR in a single day (one-stop-shop, OSS). Methods and Materials: Ten patients with small lung tumors eligible for single fraction treatments were included. The OSS procedure consisted of consultation, treatment simulation, treatment planning and delivery. Following SABR delivery, patients completed a reported experience measure (PREM) questionnaire. Prescribed doses ranged 28-34 Gy. Median GTV was 2.2 cm Results: All 10 patients completed the OSS procedure in a single day, and all reported satisfaction with the process. Median time for the treatment planning step and the whole procedure were 2.8 h and 6.6 h, respectively. With optimization of the procedure, treatment could be completed in half a day. During beam-on, the 3 mm tracking boundary encompassed between 78.0 and 100 % of the GTV across all patients, with corresponding PTV values being 94.4-100 % (5th-95th percentiles). On average, system-latency for triggering a beam-off event comprised 5.3 % of the delivery time. Latency reduced GTV coverage by an average of -0.3 %. Duty-cycles during treatment delivery ranged from 26.1 to 64.7 %. Conclusions: An OSS procedure with MR-guided SABR for lung cancer led to good patient satisfaction. Gated treatment delivery was highly accurate with little impact of system-latency.

Indexed as

Breath-holdIntra-fractionLung SBRTMotion ManagementMR-guidedSame-day treatmentSingle Fraction

Identifiers

PMID36217429
PMCPMC9547277
OpenAlexW4300773677

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.