Evidence map›Paper›PMID 36217370›Full record

ArticleNetwork science (Cambridge University Press)2022

Generating weighted and thresholded gene coexpression networks using signed distance correlation.

Javier Pardo-Diaz, Philip S Poole, Mariano Beguerisse-Díaz, Charlotte M Deane, Gesine Reinert

Abstract read
In one paragraph

Article in Network science (Cambridge University Press), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Javier Pardo-DiazDepartment of Statistics, University of Oxford, Oxford OX1 3LB, UK.
Philip S PooleDepartment of Plant Sciences, University of Oxford, Oxford OX1 3RB, UK.
Mariano Beguerisse-DíazMathematical Institute, University of Oxford, Oxford OX2 6GG, UK.
Charlotte M DeaneDepartment of Statistics, University of Oxford, Oxford OX1 3LB, UK.
Gesine ReinertDepartment of Statistics, University of Oxford, Oxford OX1 3LB, UK.

Funding

Biotechnology and Biological Sciences Research Council BB/T001801/1
6 · The paper itself

Abstract

Even within well-studied organisms, many genes lack useful functional annotations. One way to generate such functional information is to infer biological relationships between genes or proteins, using a network of gene coexpression data that includes functional annotations. Signed distance correlation has proved useful for the construction of unweighted gene coexpression networks. However, transforming correlation values into unweighted networks may lead to a loss of important biological information related to the intensity of the correlation. Here we introduce a principled method to construct

Indexed as

correlationGene expressionrobustnessweighted networks

Identifiers

PMID36217370
PMCPMC7613200

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.