Evidence map›Paper›PMID 36217339›Full record

ArticleMolecular biology2022

Oncolytic Viruses in the Therapy of Lymphoproliferative Diseases.

P O Vorobyev, F E Babaeva, A V Panova, J Shakiba, S K Kravchenko, A V Soboleva, A V Lipatova

Open access · hybridAbstract read
In one paragraph

Article in Molecular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

P O VorobyevEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
F E BabaevaNational Medical Research Center for Hematology, Ministry of Health of Russia, 125167 Moscow, Russia.
A V PanovaVavilov Institute of General Genetics, Russian Academy of Sciences, 117971 Moscow, Russia.
J ShakibaMoscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia.
S K KravchenkoNational Medical Research Center for Hematology, Ministry of Health of Russia, 125167 Moscow, Russia.
A V SobolevaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
A V LipatovaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Engelhardt Institute of Molecular Biology · RUMinistry of Health of the Russian Federation · RUMoscow Institute of Physics and Technology · RUVavilov Institute of General Genetics · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is a leading causes of death. Despite significant success in the treatment of lymphatic system tumors, the problems of relapse, drug resistance and effectiveness of therapy remain relevant. Oncolytic viruses are able to replicate in tumor cells and destroy them without affecting normal, healthy tissues. By activating antitumor immunity, viruses are effective against malignant neoplasms of various nature. In lymphoproliferative diseases with a drug-resistant phenotype, many cases of remissions have been described after viral therapy. The current level of understanding of viral biology and the discovery of host cell interaction mechanisms made it possible to create unique strains with high oncoselectivity widely used in clinical practice in recent years.

Indexed as

clinical trialslymphoproliferative diseasesoncolytic virusesspontaneous remissionvirotherapy

Identifiers

PMID36217339
PMCPMC9534467
OpenAlexW4302023679

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.