ReviewCellular and molecular neurobiology2023
Pathophysiology, Diagnosis, Treatment, and Genetics of Carpal Tunnel Syndrome: A Review.
Review in Cellular and molecular neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 32 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Relationship Between Ocular Pseudoexfoliation Syndrome and Carpal Tunnel Syndrome
Hematological and Metabolic Markers in Carpal Tunnel Syndrome
Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Comparing the efficacy of ultrasound-guided versus anatomical localization for corticosteroid injection in the treatment of carpal tunnel syndrome: a systematic review and meta-analysis.Langenbeck's archives of surgery · 2025Pooled it
- Pooled it
- Meta-analysis on effects of lymphatic drainage techniques in the management of carpal tunnel syndrome.Journal of orthopaedic surgery and research · 2025Pooled it
- Influence of Demographic Factors on Presentation, Symptoms and Function in Carpal Tunnel Syndrome.Healthcare (Basel, Switzerland) · 2026Article
- Ultrasoft, adhesive, pH-tunable hydrogel based on in situ functionalized laser-induced graphene for through-hair concurrent biosensing.Science advances · 2026Article
- Article
- Acetyl-L-Carnitine in the Treatment of Peripheral Neuropathies: A Narrative Review.Pain and therapy · 2026Review
- Median nerve swelling in RA patients: an 8-year longitudinal MRI-based study.Insights into imaging · 2026Article
- Surgical Versus Conservative Management for Carpal Tunnel Syndrome: An Updated Systematic Review of Randomised Trials.Brain sciences · 2026Review
- Ultrasound-Guided Percutaneous Needle Electrolysis Versus Surgery for Carpal Tunnel Syndrome: A Randomized Clinical Trial.Healthcare (Basel, Switzerland) · 2026Article
- Ultrasound-guided hydrodissection combined with acupotomy for moderate-to-severe Carpal tunnel syndrome: electrophysiological and ultrasonographic outcomes and their potential relationship to neuroinflammatory attenuation.Frontiers in cell and developmental biology · 2026Article
- Ultrasound-Guided Low-Level He-Ne Laser Therapy Following Acupotomy Release for Carpal Tunnel Syndrome: A Multicenter Retrospective Study.Journal of pain research · 2026Article
- Translation, Cross-Cultural Adaptation and Psychometric Validation of the Romanian Version of the Boston Carpal Tunnel Questionnaire.Diagnostics (Basel, Switzerland) · 2025Article
- [Effect of needle-knife release on the median nerve and transverse carpal ligament in rabbits with carpal tunnel syndrome].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025Article
- Carpal Tunnel Syndrome at the Intersection of Internal Medicine, Gastroenterology, and Neurology: A Thorough Examination.Journal of clinical medicine · 2025Article
- Carpal Tunnel Syndrome: A Comprehensive Review.Cureus · 2025Review
- Occupational biomechanical risk factors for carpal tunnel syndrome surgery: a prospective cohort study on 203 866 Swedish male construction workers followed for 19 years.Occupational and environmental medicine · 2025Article
- Comparison of ultrasound and magnetic resonance imaging of the median nerve's recurrent motor branch and the value of its diameter in diagnosing carpal tunnel syndrome.Quantitative imaging in medicine and surgery · 2025Article
- Intraoperative change in distal motor latency as a predictor for clinical outcome after mini-OCTR: a retrospective cohort study.Frontiers in neurology · 2025Article
- Predictors for Postoperative Nerve Recovery in Severe Carpal Tunnel Syndrome.Journal of pain research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Carpal tunnel syndrome (CTS) is a common peripheral canalicular nerve entrapment syndrome in the upper extremities. The compression of or injury to the median nerve at the wrist as it passes through a space-limited osteofibrous carpal canal can cause CTS, resulting in hand pain and impaired function. The present paper reviews the literature on the prevalence, pathology, diagnosis, treatment, and risk factors of CTS in conjunction with the role of genetic factors in CTS etiology. CTS diagnosis is primarily linked with clinical symptoms; still, it is simplified by sophisticated approaches such as magnetic resonance imaging and ultrasonography. CTS symptoms can be ameliorated through conservative and surgical strategies. The exact CTS pathophysiology needs clarification. Genetic predispositions to CTS are augmented by various variants within genes; however, CTS etiology could include risk factors such as wrist movements, injury, and specific conditions (e.g., age, body mass index, sex, and cardiovascular conditions). The high prevalence of CTS diminishes the quality of life of its sufferers and imposes costs on health systems, hence the significance of research and clinical trials to elucidate CTS pathogenesis and develop novel therapeutic targets.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.