Evidence map›Paper›PMID 36217013›Full record

ArticleScientific reports2022

Development and large-scale validation of the Watch Walk wrist-worn digital gait biomarkers.

Lloyd L Y Chan, Tiffany C M Choi, Stephen R Lord, Matthew A Brodie

Erratum issuedAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  5. Observational
  6. Are Real-World Mobility Patterns Early Indicators of COPD Onset? Insights from Wrist-Worn Sensors.International journal of chronic obstructive pulmonary disease · 2026
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  10. Comparing Step-Counting Algorithms for High-Resolution Wrist Accelerometry Data in Older Adults in the ARIC Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Lloyd L Y ChanFalls, Balance and Injury Research Centre, Neuroscience Research Australia, 139 Baker Street, Randwick, NSW, 2031, Australia.
Tiffany C M ChoiSchool of Health Sciences, Caritas Institute of Higher Education, 2 Chui Ling Lane, New Territories, Tseung Kwan O, Hong Kong, China.
Stephen R LordFalls, Balance and Injury Research Centre, Neuroscience Research Australia, 139 Baker Street, Randwick, NSW, 2031, Australia. s.lord@neura.edu.au.
Matthew A BrodieFalls, Balance and Injury Research Centre, Neuroscience Research Australia, 139 Baker Street, Randwick, NSW, 2031, Australia.

Funding

Medical Research Council MC_PC_17228Medical Research Council MC_QA137853
6 · The paper itself

Abstract

Digital gait biomarkers (including walking speed) indicate functional decline and predict hospitalization and mortality. However, waist or lower-limb devices often used are not designed for continuous life-long use. While wrist devices are ubiquitous and many large research repositories include wrist-sensor data, widely accepted and validated digital gait biomarkers derived from wrist-worn accelerometers are not available yet. Here we describe the development of advanced signal processing algorithms that extract digital gait biomarkers from wrist-worn devices and validation using 1-week data from 78,822 UK Biobank participants. Our gait biomarkers demonstrate good test-retest-reliability, strong agreement with electronic walkway measurements of gait speed and self-reported pace and significantly discriminate individuals with poor self-reported health. With the almost universal uptake of smart-watches, our algorithms offer a new approach to remotely monitor life-long population level walking speed, quality, quantity and distribution, evaluate disease progression, predict risk of adverse events and provide digital gait endpoints for clinical trials.

Indexed as

GaitWristBiomarkersHumansReproducibility of ResultsWalkingBiomarkers

Identifiers

PMID36217013
PMCPMC9551062

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.