Evidence map›Paper›PMID 36216962›Full record

ArticleArchives of osteoporosis2022

Bone mineral density, nutrient intake, and physical activity among young women from Uganda.

Renee Heffron, Timothy R Muwonge, Jade Boyer, Flavia Matovu, Yasaman Zia, Monica Bagaya, Timothy Ssebuliba, Susan Morrison, Felix Bambia, Rogers Nsubuga and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of osteoporosis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Renee HeffronDepartment of Global Health, University of Washington, Box 359927 325 Ninth Ave, Seattle, WA, USA. rheffron@uabmc.edu.ORCID https://orcid.org/0000-0001-6039-0352
Timothy R MuwongeInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Jade BoyerDepartment of Global Health, University of Washington, Box 359927 325 Ninth Ave, Seattle, WA, USA.
Flavia MatovuMakerere University-Johns Hopkins University Research Collaboration, Kampala, Uganda.
Yasaman ZiaDepartment of Global Health, University of Washington, Box 359927 325 Ninth Ave, Seattle, WA, USA.
Monica BagayaInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Timothy SsebulibaInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Susan MorrisonDepartment of Global Health, University of Washington, Box 359927 325 Ninth Ave, Seattle, WA, USA.
Felix BambiaInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Rogers NsubugaInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Josephine BadaruInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Gabrielle SteinDepartment of Global Health, University of Washington, Box 359927 325 Ninth Ave, Seattle, WA, USA.
Kenneth K MugwanyaDepartment of Global Health, University of Washington, Box 359927 325 Ninth Ave, Seattle, WA, USA.
Christina WyattDepartment of Medicine, Division of Nephrology, Duke University School of Medicine, Durham, NC, USA.
Jared M BaetenDepartment of Global Health, University of Washington, Box 359927 325 Ninth Ave, Seattle, WA, USA.
Michael T YinDepartment of Medicine, Division of Infectious Diseases, Columbia University Irving Medical Center, New York, NY, USA.
Andrew MujugiraDepartment of Global Health, University of Washington, Box 359927 325 Ninth Ave, Seattle, WA, USA.
Kampala Women’s Bone Study Team

Funding

Impact of Concurrent Initiation of DMPA Contraception and Tenofovir PrEP on Bone Loss in Young WomenR01HD089843 · NICHD · UNIVERSITY OF WASHINGTON · PI HEFFRON, RENEE A. · 2017 to 2021
$3.9M
Bone mass and mineral metabolism in HIV+ womenK23AI059884 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI YIN, MICHAEL T · 2004 to 2008
$647k
NICHD NIH HHS R01 HD089843
6 · The paper itself

Abstract

Few studies have characterized bone mineral density (BMD) among health young African women. In our study of 496 Ugandan women age ≤25 years, we found that women had healthy BMD that were lower on average than the standard reference ranges. Reference ranges available for BMD measurements need greater precision. PURPOSE: Data describing bone mineral density (BMD), nutrient intake, and body composition among healthy, young women in sub-Saharan Africa are limited. Using baseline data from a cohort of young, healthy Ugandan women, we summarize bone health and associated risk factors for reduced bone mass.

methodsUsing baseline data from Ugandan women ages 16-25 years who enrolled in an ongoing cohort study of bone health with concurrent use of injectable contraception and oral HIV pre-exposure prophylaxis, we describe the distribution of BMD, nutrient intake, physical activity, and body composition. The association of low BMD (1 or more standard deviations below the age, sex, and race-matched reference range from the USA) and calcium intake, vitamin D intake, physical activity, and body composition was estimated using multivariable logistic regression.

resultsIn 496 healthy, Ugandan women with median age of 20 years (interquartile range [IQR] 19-21) and median fat:lean mass ratio of 0.55 (IQR 0.46-0.64), median lumbar spine and total hip BMD was 0.9g/cm

conclusionYoung Ugandan women exhibited healthy levels of BMD that were lower than the reference range population.

Indexed as

Bone DensityCalciumAbsorptiometry, PhotonAdolescentAdultBody Mass IndexCohort StudiesEatingExerciseFemaleHumansLumbar VertebraeUgandaVitamin DYoung AdultCalciumVitamin DBone mineral densityCalciumPhysical activityUgandaWomen

Identifiers

PMID36216962
PMCPMC11262243

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.