SynthesisNature medicine2022
Health effects associated with consumption of unprocessed red meat: a Burden of Proof study.
Synthesis in Nature medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
76 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Systematic Analysis of the Differential Effects of Red Meat on Colorectal Cancer Risks: A Meta-Analytic Approach.Journal of gastrointestinal cancer · 2025Pooled it
- The health effects associated with physical, sexual and psychological gender-based violence against men and women: a Burden of Proof study.Nature human behaviour · 2025Pooled it
- Health effects associated with exposure of children to physical violence, psychological violence and neglect: a Burden of Proof study.Nature human behaviour · 2025Pooled it
- A systematic review with a Burden of Proof meta-analysis of health effects of long-term ambient fine particulate matter (PMNature aging · 2025Pooled it
- Health effects associated with chewing tobacco: a Burden of Proof study.Nature communications · 2024Pooled it
- Effects of meat-based, meat-based with α-tocopherol, and pesco-vegetarian diets on biomarkers associated with colorectal cancer risk: a randomized behavioral intervention trial.Scientific reports · 2025Trial
- Assessment of Vascular Function in Response to High-Fat and Low-Fat Ground Beef Consumption in Men.Nutrients · 2023Trial
- Diet, gut microbiome, and type 1 diabetes: from risk to translational opportunity.Gut microbes · 2026Review
- Plant and Animal Protein Sources in Inflammatory Bowel Disease: Current Evidence and Clinical Implications.JGH open : an open access journal of gastroenterology and hepatology · 2026Review
- Mitigating lipid oxidation in meat products using nano-formulated essential oils and plant extracts: a systematic review.Food chemistry: X · 2026Review
- The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of gut health.Nature reviews. Gastroenterology & hepatology · 2026Article
- Increased vulnerability of colorectal cancer models with high alkylation damage to NTHL1 inactivation.Scientific reports · 2026Article
- A Heatmap-Based Risk-Benefit Assessment of Traditional and Processed Meat Products.Foods (Basel, Switzerland) · 2026Review
- The burden of dietary risk factors in the Nordic and Baltic countries: a systematic analysis for the Global Burden of Disease Study 2023.The Lancet regional health. Europe · 2026Article
- Global burden of dietary-related mortality in working-age population, 1990-2021: trends and disparities across 204 countries and territories.European journal of nutrition · 2026Article
- Investigating eating patterns and risk factors of weight status among undergraduate students in a multinational cross-sectional study across 15 countries with 8,482 participants.BMC public health · 2026Article
- Multi-objective optimization of national dietary guidelines: balancing nutrition, environment, and economy.Frontiers in nutrition · 2026Article
- Health effects associated with alcohol consumption: a Burden of Proof study.Nature health · 2026Article
- Isocaloric substitution with beef and mutton and metabolically unhealthy obesity among adults in Ordos, Inner Mongolia: a cross-sectional analysis.Frontiers in nutrition · 2026Article
- The Mediterranean Diet as a Model of Sustainability: Evidence-Based Insights into Health, Environment, and Culture.International journal of environmental research and public health · 2025Review
16 more citing papers are in PubMed but not listed here.
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Authors and funding
18 authors.
Funding
Abstract
Characterizing the potential health effects of exposure to risk factors such as red meat consumption is essential to inform health policy and practice. Previous meta-analyses evaluating the effects of red meat intake have generated mixed findings and do not formally assess evidence strength. Here, we conducted a systematic review and implemented a meta-regression-relaxing conventional log-linearity assumptions and incorporating between-study heterogeneity-to evaluate the relationships between unprocessed red meat consumption and six potential health outcomes. We found weak evidence of association between unprocessed red meat consumption and colorectal cancer, breast cancer, type 2 diabetes and ischemic heart disease. Moreover, we found no evidence of an association between unprocessed red meat and ischemic stroke or hemorrhagic stroke. We also found that while risk for the six outcomes in our analysis combined was minimized at 0 g unprocessed red meat intake per day, the 95% uncertainty interval that incorporated between-study heterogeneity was very wide: from 0-200 g d
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.