ArticleScientific reports2022
Analysis of the robustness and dynamics of spin-locking preparations for the detection of oscillatory magnetic fields.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Stimulus-induced rotary saturation imaging of visually evoked response: A pilot study.NMR in biomedicine · 2025Article
- Neuronal current imaging of epileptic activity: An MRI study in patients with a first unprovoked epileptic seizure.Epilepsia open · 2024Observational
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4 authors.
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Abstract
Extracting quantitative information of neuronal signals by non-invasive imaging is an outstanding challenge for understanding brain function and pathology. However, state-of-the-art techniques offer low sensitivity to deep electrical sources. Stimulus induced rotary saturation is a recently proposed magnetic resonance imaging sequence that detects oscillatory magnetic fields using a spin-lock preparation. Phantom experiments and simulations proved its efficiency and sensitivity, but the susceptibility of the method to field inhomogeneities is still not well understood. In this study, we simulated and analyzed the dynamic of three spin-lock preparations and their response to field inhomogeneities in the presence of a resonant oscillating field. We show that the composite spin-lock preparation is more robust against field variations within the double resonance effect. In addition, we tested the capability of the chosen composite spin-lock preparation to recover information about the spectral components of a composite signal. This study sets the bases to move one step further towards the clinical application of MR-based neuronal current imaging.
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