Evidence map›Paper›PMID 36216717›Full record

ArticleTrends in immunology2022

Cutting edge: interleukin-17a prompts HIF1α for wound healing.

Minhal Ahmed, Jun R Huh

Abstract readComment
PubMed Publisher
In one paragraph

Article in Trends in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. IL-17 in wound repair: bridging acute and chronic responses.Cell communication and signaling : CCS · 2024
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Minhal AhmedHarvard-MIT Health Sciences and Technology Program, Harvard Medical School, Boston, MA, USA; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Jun R HuhDepartment of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. Electronic address: Jun_Huh@hms.harvard.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IL-17a is widely considered an inflammatory cytokine, linked to the development and severity of autoimmune diseases such as inflammatory bowel disease and psoriasis. However, a recent report by Konieczny et al. sheds light on a novel protective role of IL-17a in wound healing, adding to the growing list of studies highlighting a noninflammatory function for IL-17a.

Indexed as

Autoimmune DiseasesPsoriasisCytokinesHumansInterleukin-17Wound HealingCytokinesInterleukin-17HIF-1αimmunoepithelialimmunometabolisminterleukin-17awound healingγδ T cells

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.