Evidence map›Paper›PMID 36216513›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2022

Cutting Edge: Neutrophils License the Maturation of Monocytes into Effective Antifungal Effectors.

Vanessa Espinosa, Orchi Dutta, Lena J Heung, Keyi Wang, Yun-Juan Chang, Patricia Soteropoulos, Tobias M Hohl, Mark C Siracusa, Amariliz Rivera

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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  12. Review
  13. Immunity to fungi in the lung.Seminars in immunology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Vanessa EspinosaCenter for Immunity and Inflammation, New Jersey Medical School, Rutgers-The State University of New Jersey, Newark, NJ.ORCID 0000-0003-4808-3557
Orchi DuttaCenter for Immunity and Inflammation, New Jersey Medical School, Rutgers-The State University of New Jersey, Newark, NJ.
Lena J HeungDepartment of Medicine, Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, CA.ORCID 0000-0002-6655-575X
Keyi WangCenter for Immunity and Inflammation, New Jersey Medical School, Rutgers-The State University of New Jersey, Newark, NJ.
Yun-Juan ChangGenomics Research Program, New Jersey Medical School, Rutgers-The State University of New Jersey, Newark, NJ.ORCID 0000-0003-2688-6391
Patricia SoteropoulosGenomics Research Program, New Jersey Medical School, Rutgers-The State University of New Jersey, Newark, NJ.
Tobias M HohlMemorial Sloan Kettering Cancer Center, New York, NY; and.ORCID 0000-0002-9097-5412
Mark C SiracusaCenter for Immunity and Inflammation, New Jersey Medical School, Rutgers-The State University of New Jersey, Newark, NJ.
Amariliz RiveraCenter for Immunity and Inflammation, New Jersey Medical School, Rutgers-The State University of New Jersey, Newark, NJ; riveraam@njms.rutgers.edu.ORCID 0000-0002-2173-5597
Rutgers, The State University of New Jersey · USCedars-Sinai Medical Center · USMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
INITIATION OF THE IMMUNE RESPONSE TO ASPERGILLUS FUMIGATUSR01AI093808 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI HOHL, TOBIAS M · 2011 to 2020
$4.9M
INITIATION OF THE IMMUNE RESPONSE TO ASPERGILLUS FUMIGATUSR37AI093808 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI TOBIAS M HOHL · 2021 to 2026
$4.2M
Trained immunity and the regulation of anti-fungal defenseR01AI169769 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Amariliz Rivera, Chaoyang Xue · 2022 to 2026
$3.1M
DAP12 and the host response to cryptococcosisR01AI162765 · NIAID · CEDARS-SINAI MEDICAL CENTER · PI HEUNG, LENA J · 2021 to 2025
$2.8M
Protective and pathologic functions of macrophages induced by helminthsR01AI131634 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI GAUSE, WILLIAM CLARK, SIRACUSA, MARK CHRISTOPHER · 2018 to 2022
$2.6M
Innate Immune regulation of helminth-induced inflammationR01AI123224 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI SIRACUSA, MARK CHRISTOPHER · 2016 to 2020
$2.0M
Regulation of antifungal immunity by monocyte-derived dendritic cellsR01AI114647 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI RIVERA, AMARILIZ · 2015 to 2019
$1.8M
Brain corticosterone and alcohol: mechanismsR01AA013932 · NIAAA · U OF L ST. GEORGE'S HOSPITAL MEDICAL SCH · PI LITTLE, HILARY J · 2003 to 2005
$837k
Inflammatory monocytes and host control of cryptococcosisK08AI130366 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI HEUNG, LENA J · 2017 to 2021
$829k
NCI NIH HHS P30 CA008748NIAAA NIH HHS R01 AA013932NIAID NIH HHS K08 AI130366NIAID NIH HHS R01 AI093808NIAID NIH HHS R01 AI114647NIAID NIH HHS R01 AI123224NIAID NIH HHS R01 AI131634NIAID NIH HHS R01 AI162765NIAID NIH HHS R01 AI169769NIAID NIH HHS R37 AI093808
6 · The paper itself

Abstract

Neutrophils are critical for the direct eradication of

Indexed as

MonocytesNeutrophilsAnimalsAntifungal AgentsAspergillus fumigatusMiceReactive Oxygen SpeciesAntifungal AgentsReactive Oxygen Species

Identifiers

PMID36216513
PMCPMC10115354
OpenAlexW4304480860

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.