Evidence map›Paper›PMID 36216507›Full record

ArticleeNeuro

A Uniform and Isotropic Cytoskeletal Tiling Fills Dendritic Spines.

Florian Eberhardt, Eric A Bushong, Sébastien Phan, Steven Peltier, Pablo Monteagudo-Mesas, Tino Weinkauf, Andreas V M Herz, Martin Stemmler, Mark Ellisman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Florian EberhardtFaculty of Biology, Ludwig-Maximilians-Universität and Bernstein Center for Computational Neuroscience Munich, Munich, Planegg-Martinsried D-82152, Germany eberhardt@bio.lmu.de mellisman@ucsd.edu.ORCID https://orcid.org/0000-0001-6268-0388
Eric A BushongDepartment of Neurosciences and National Center for Microscopy and Imaging Research, Center for Research in Biological Systems, University of California, San Diego, La Jolla, 92093 CA.
Sébastien PhanDepartment of Neurosciences and National Center for Microscopy and Imaging Research, Center for Research in Biological Systems, University of California, San Diego, La Jolla, 92093 CA.
Steven PeltierDepartment of Neurosciences and National Center for Microscopy and Imaging Research, Center for Research in Biological Systems, University of California, San Diego, La Jolla, 92093 CA.
Pablo Monteagudo-MesasFaculty of Biology, Ludwig-Maximilians-Universität and Bernstein Center for Computational Neuroscience Munich, Munich, Planegg-Martinsried D-82152, Germany.
Tino WeinkaufSchool of Electrical Engineering and Computer Science, KTH Royal Institute of Technology, Stockholm, 100 44 Sweden.
Andreas V M HerzFaculty of Biology, Ludwig-Maximilians-Universität and Bernstein Center for Computational Neuroscience Munich, Munich, Planegg-Martinsried D-82152, Germany.ORCID https://orcid.org/0000-0002-3836-565X
Martin StemmlerFaculty of Biology, Ludwig-Maximilians-Universität and Bernstein Center for Computational Neuroscience Munich, Munich, Planegg-Martinsried D-82152, Germany.
Mark EllismanDepartment of Neurosciences and National Center for Microscopy and Imaging Research, Center for Research in Biological Systems, University of California, San Diego, La Jolla, 92093 CA eberhardt@bio.lmu.de mellisman@ucsd.edu.
Bernstein Center for Computational Neuroscience Munich · DEUniversity of California San Diego · USKTH Royal Institute of Technology · SE

Funding

IVEM and Image Analysis ResourceP41GM103412 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ELLISMAN, MARK H · 2012 to 2019
$17.9M
National Center for Microscopy and Imaging Research: A BRAIN Technology Integration and Dissemination ResourceU24NS120055 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ELLISMAN, MARK H · 2021 to 2025
$5.4M
The National Center for Microscopy and Imaging Research, a Community-wide Scientific ResourceR24GM137200 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ELLISMAN, MARK H · 2020 to 2022
$3.0M
FEI TITAN HALO 300kV INTERMEDIATE VOLTAGE ELECTRON MICROSCOPES10OD021784 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ELLISMAN, MARK H · 2017 to 2017
$1.9M
CRCNS: Deciphering the Dynamical Multi-Scale Structure-Function Relation of Dendritic SpinesR01DA038896 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ELLISMAN, MARK H · 2014 to 2018
$887k
NIDA NIH HHS R01 DA038896NIGMS NIH HHS P41 GM103412NIGMS NIH HHS R24 GM137200NIH HHS S10 OD021784NINDS NIH HHS U24 NS120055
6 · The paper itself

Abstract

Dendritic spines are submicron, subcellular compartments whose shape is defined by actin filaments and associated proteins. Accurately mapping the cytoskeleton is a challenge, given the small size of its components. It remains unclear whether the actin-associated structures analyzed in dendritic spines of neurons

Indexed as

ActinsDendritic SpinesAnimalsCytoskeletonHippocampusMaleMiceNeuronsActinsactin cytoskeletoncerebellar Purkinje celldendritic spines in situEM tomographyhippocampal pyramidal cellimage segmentation

Identifiers

PMID36216507
PMCPMC9617608
OpenAlexW4304086861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.