Evidence map›Paper›PMID 36216506›Full record

ArticleeNeuro

Oral Sensory Neurons of the Geniculate Ganglion That Express Tyrosine Hydroxylase Comprise a Subpopulation That Contacts Type II and Type III Taste Bud Cells.

Tao Tang, Brian A Pierchala

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Axonal mapping of the motor cranial nerves.Frontiers in neuroanatomy · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Tao TangDepartment of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, Stark Neurosciences Research Institute, Indianapolis, IN 46202.
Brian A PierchalaDepartment of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, Stark Neurosciences Research Institute, Indianapolis, IN 46202 brpierch@iu.edu.
Indiana University · USIndiana University School of Medicine

Funding

Growth factors in the development and physiology of geniculate taste neuronsR01DC015799 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Brian Anthony Pierchala · 2017 to 2026
$4.8M
NIDCD NIH HHS R01 DC015799
6 · The paper itself

Abstract

Oral sensory neurons of the geniculate ganglion (GG) innervate taste papillae and buds on the tongue and soft palate. Electrophysiological recordings of these neurons and fibers revealed complexity in the number of unique response profiles observed, suggesting there are several distinct neuronal subtypes. Molecular descriptions of these subpopulations are incomplete. We report here the identification of a subpopulation of GG oral sensory neurons in mice by expression of tyrosine hydroxylase (TH). TH-expressing geniculate neurons represent 10-20% of oral sensory neurons and these neurons innervate taste buds in fungiform and anterior foliate taste papillae on the surface of the tongue, as well as taste buds in the soft palate. While 35-50% of taste buds on the tongue are innervated by these TH+ neurons, 100% of soft palate taste buds are innervated. These neurons did not have extragemmal processes outside of taste buds and did not express the mechanosensory neuron-associated gene

Indexed as

Taste BudsAnimalsGeniculate GanglionMiceSensory Receptor CellsTasteTongueTyrosine 3-MonooxygenaseTyrosine 3-Monooxygenasechemosensory neurongeniculate gangliongustatorytastetaste budtyrosine hydroxylase

Identifiers

PMID36216506
PMCPMC9581578
OpenAlexW4304086877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.