Evidence map›Paper›PMID 36216202›Full record

ReviewCurrent problems in cardiology2023

Nationwide Analysis of the Outcomes and Mortality of Hospitalized COVID-19 Patients.

Ameesh Isath, Aaqib H Malik, Akshay Goel, Rahul Gupta, Rishi Shrivastav, Dhrubajyoti Bandyopadhyay

Abstract readReview
In one paragraph

Review in Current problems in cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Factors Associated With Shifts in Caregiving During COVID-19.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2025
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  13. From test to rest: evaluating socioeconomic differences along the COVID-19 care pathway in the Netherlands.The European journal of health economics : HEPAC : health economics in prevention and care · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ameesh IsathDepartment of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, NY.
Aaqib H MalikDepartment of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, NY.
Akshay GoelDepartment of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, NY.
Rahul GuptaLehigh Valley Heart Institute, Lehigh Valley Health Network, Allentown, PA.
Rishi ShrivastavMount Sinai St. Luke's-BronxCare, New York, NY.
Dhrubajyoti BandyopadhyayDepartment of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, NY. Electronic address: drdhrubajyoti87@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe Coronavirus disease 2019 (COVID-19) pandemic has affected people worldwide with the United States (US) with the largest number of reported cases currently. Previous studies in hospitalized COVID-19 patients have been limited by sample size.

methodsThe National Inpatient Sample database which is the largest inpatient database in the US was queried in the year 2020 for the diagnosis of COVID-19 based on ICD-10-CM U07.1 and associated outcomes. Multivariate logistic regression analysis was used to identify predictors of mortality. STATA 16.0 was used for statistical analysis.

resultsA weighted total of 1,678,995 hospitalizations for COVID-19 were identified. Median age of admitted patients with COVID-19 was 65 year (51-77) with 47.9% female and 49.2% White. Majority of the patients admitted were >65 years of age (49.3%). Hypertension and diabetes were the most common comorbidities (64.2% and 39.5%, respectively). Overall inpatient mortality was 13.2% and increasing to 55.9% in patients requiring mechanical ventilation. Trend of inpatient mortality was significantly decreasing over the year. Predictors of inpatient mortality included age, male sex, diabetes, chronic kidney disease, heart failure, arrythmia, obesity, and coagulopathy. Despite a lower proportion of patients admitted to hospital with COVID-19, Black, Hispanic, and Native Americans were at an increased adjusted odds of inpatient mortality. Disparity was also noted in income, with low median household income associated with higher risk of mortality.

conclusionIn the largest US cohort with >1.6 million hospitalized COVID-19 patients in 2020, overall inpatient mortality was 13.6% with significantly higher mortality in ventilated patients. Significant socioeconomic and racial disparities were present with minorities at higher odds of mortality.

Indexed as

COVID-19Diabetes MellitusComorbidityFemaleHospitalizationHumansMaleObesityUnited States

Identifiers

PMID36216202
PMCPMC9546497

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.