Evidence map›Paper›PMID 36215911›Full record

Observational studyJournal of substance abuse treatment2022

Acceptability, feasibility, and outcomes of a clinical pilot program for video observation of methadone take-home dosing during the COVID-19 pandemic.

Kevin A Hallgren, James Darnton, Sean Soth, Kendra L Blalock, Alyssa Michaels, Paul Grekin, Andrew J Saxon, Steve Woolworth, Judith I Tsui

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of substance abuse treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kevin A HallgrenUniversity of Washington School of Medicine, Department of Psychiatry and Behavioral Sciences, Seattle, WA 98195, United States. Electronic address: khallgre@uw.edu.
James DarntonUniversity of Washington, Division of General Internal Medicine, Seattle, WA 98195, United States; Evergreen Treatment Services, Seattle, WA 98134, United States.
Sean SothEvergreen Treatment Services, Seattle, WA 98134, United States.
Kendra L BlalockUniversity of Washington, Division of General Internal Medicine, Seattle, WA 98195, United States.
Alyssa MichaelsUniversity of Washington, Division of General Internal Medicine, Seattle, WA 98195, United States.
Paul GrekinUniversity of Washington School of Medicine, Department of Psychiatry and Behavioral Sciences, Seattle, WA 98195, United States; Evergreen Treatment Services, Seattle, WA 98134, United States.
Andrew J SaxonUniversity of Washington School of Medicine, Department of Psychiatry and Behavioral Sciences, Seattle, WA 98195, United States; Center of Excellence in Substance Addiction Treatment and Education (CESATE), VA Puget Sound Health Care System, Seattle, WA 98108, United States.
Steve WoolworthEvergreen Treatment Services, Seattle, WA 98134, United States.
Judith I TsuiUniversity of Washington, Division of General Internal Medicine, Seattle, WA 98195, United States.
University of Washington · USPerinatal Treatment Services · US

Funding

Developing a tool to assess, provide feedback, and facilitate discussion of mechanisms of change in frontline addiction treatmentK01AA024796 · NIAAA · UNIVERSITY OF WASHINGTON · PI HALLGREN, KEVIN A. · 2016 to 2020
$870k
Feasibility of mHealth technology-enabled service for remote observed therapy of methadone and COVID-19 screening for patients in an opioid treatment programR41DA053081 · NIDA · EMOCHA MOBILE HEALTH, INC. · PI SEIGUER, SEBASTIAN, TSUI, JUDITH · 2020 to 2020
$225k
NIAAA NIH HHS K01 AA024796NIDA NIH HHS R41 DA053081
6 · The paper itself

Abstract

backgroundMethadone is one of the most utilized treatments for opioid use disorder. However, requirements for observing methadone dosing can impose barriers to patients and increase risk for respiratory illness transmission (e.g., COVID-19). Video observation of methadone dosing at home could allow opioid treatment programs (OTPs) to offer more take-home doses while ensuring patient safety through remote observation of ingestion.

methodsBetween April and August 2020, a clinical pilot program of video observation of methadone take-home dosing via smartphone was conducted within a multisite OTP agency. Participating patients completed a COVID-19 symptom screener and submitted video recordings of themselves ingesting all methadone take-home doses. Patients who followed these procedures for a two-week trial period could continue participating in the full pilot program and potentially receive more take-home doses. This retrospective observational study characterizes patient engagement and compares clinical outcomes with matched controls.

resultsOf 44 patients who initiated the two-week trial, 33 (75 %) were successful and continued participating in the full pilot program. Twenty full pilot participants (61 %) received increased take-home doses. Full pilot participants had more days with observed dosing over a 60-day period than matched controls (mean = 53.2 vs. 16.6 days, respectively). Clinical outcomes were similar between pilot participants and matched controls.

conclusionsVideo observation of methadone take-home dosing implemented during the COVID-19 pandemic was feasible. This model has the potential to enhance safety by increasing rates of observed methadone dosing and reducing infection risks and barriers associated with relying solely on face-to-face observation of methadone dosing.

Indexed as

COVID-19Opioid-Related DisordersAnalgesics, OpioidFeasibility StudiesHumansMethadoneOpiate Substitution TreatmentPandemicsPilot ProjectsAnalgesics, OpioidMethadoneMethadonemHealthOpioid treatment programsRemote therapeutic monitoringVideo directly observed therapy

Identifiers

PMID36215911
PMCPMC9531364
OpenAlexW4300981404

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.