Evidence map›Paper›PMID 36215800›Full record

ArticleJournal of infection and public health2022

COVID-19 vaccine had a significant positive impact on patients with SARS-COV-2 during the third (Omicron) wave in Saudi Arabia.

Salma AlBahrani, Ali AlBarrak, Tariq Al-Musawi, Nawal Ali AlGubaisi, Maram Almalki, Fatimah H Hakami, Turki Alghamdi, Zena AlBeiuruti, Sausan Alkhrashi, Meshael Almershad and 5 more

Abstract read
In one paragraph

Article in Journal of infection and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
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  7. Jugan geon-gang gwa jilbyeong · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Salma AlBahraniInfectious Disease Unit, Specialty Internal Medicine, King Fahd Military Medical Complex, Dhahran, Saudi Arabia.
Ali AlBarrakInfectious Disease Division, Internal Medicine Department, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Tariq Al-MusawiCritical Care Department, Dr. Sulaiman Alhabib Hospital, Alkhobar, Saudi Arabia; Royal College of Surgeons in Ireland-Medical University of Bahrain, Bahrain.
Nawal Ali AlGubaisiKing Fahd Military Medical Complex, Dhahran, Saudi Arabia.
Maram AlmalkiKing Fahd Military Medical Complex, Dhahran, Saudi Arabia.
Fatimah H HakamiKing Fahd Military Medical Complex, Dhahran, Saudi Arabia.
Turki AlghamdiKing Fahd Military Medical Complex, Dhahran, Saudi Arabia.
Zena AlBeiurutiKing Fahd Military Medical Complex, Dhahran, Saudi Arabia.
Sausan AlkhrashiKing Fahd Military Medical Complex, Dhahran, Saudi Arabia.
Meshael AlmershadKing Fahd Military Medical Complex, Dhahran, Saudi Arabia.
Samira AlzahraniKing Fahd Military Medical Complex, Dhahran, Saudi Arabia.
Amerah AlQuraiaanKing Fahd Military Medical Complex, Dhahran, Saudi Arabia.
Helmy AlTourifiKing Fahd Military Medical Complex, Dhahran, Saudi Arabia.
Arulanantham Zechariah JebakumarVice Deanship of Postgraduate Studies and Research, Prince Sultan Military College of Health Sciences, Dhahran, Saudi Arabia.
Jaffar A Al-TawfiqInfectious Disease Unit, Specialty Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia; Infectious Disease Division, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA; Infectious Disease Division, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: jaffar.tawfiq@jhah.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe third (Omicron) wave had caused significant increase in the number of COVID-19 cases around the globe. The severity of the disease dependeds on the extent of the vaccination status.

methodsThis is a retrospective study of infected COVID-19 patients during the third (Omicron) wave in a hospital in Saudi Arabia.

resultsA total of 400 patients were included with 220 (55 %) males and 180 (45 %) females, and a mean age (+/- SD) of 36.34 + 16.47 years. The most common presenting symptoms were: sore throat 159 (39.8 %), cough 158 (39.5 %), fever 132 (33 %), headache 122 (30.5 %), and muscle ache 124 (31%). There was no difference in underlying conditions, signs and symptoms between males and females apart from the occurrence of sore throat with an OR of 2.014 (95 % CI: 1.103-3.677, P = 0.023) and need of hospitalization OR 2.457 (95 % CI: 1.168-5.167, P value =.018) in a binary logistic regression comparison. The need for hospitalization was inversely related to the number of COVID-19 vaccination doses. The rate of admission was 8 (72.7 %), 34 (12 %), 4 (5.4 %) for one, two, and three doses of COVID-19 vaccine, respectively (P < 0.0001). Of all the patients, 14 (3.5 %) and 8 (2 %) required intensive care (ICU) admission and mechanical ventilation, respectively. The median Ct-value of SARS-CoV-2 was higher in those who had 2 or 3 doses compared to those who had one dose of the COVID-19 vaccine, but the difference did not reach statistical significance. None of the included patients died during the study period.

conclusionOmicron variant symptoms among infected patients are generally milder compared to other variants. Prior COVID-19 vaccination may limit disease severity and need for hospitalization.

Indexed as

COVID-19PharyngitisAdultCOVID-19 VaccinesFemaleHumansMaleMiddle AgedPainRetrospective StudiesSARS-CoV-2Saudi ArabiaYoung AdultCOVID-19 VaccinesCOVID-19OmicronSARS-CoV-2Saudi ArabiaThird waveVaccine

Identifiers

PMID36215800
PMCPMC9490953

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.