Evidence map›Paper›PMID 36215670›Full record

ArticleACS chemical biology2023

Discovery of Homogentisic Acid as a Precursor in Trimethoprim Metabolism and Natural Product Biosynthesis.

Andrew C McAvoy, Paxton H Threatt, Joseph Kapcia, Neha Garg

Abstract read
In one paragraph

Article in ACS chemical biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Andrew C McAvoySchool of Chemistry and Biochemistry, Georgia Institute of Technology, 950 Atlantic Drive, Atlanta, Georgia 30332-2000, United States.
Paxton H ThreattSchool of Chemistry and Biochemistry, Georgia Institute of Technology, 950 Atlantic Drive, Atlanta, Georgia 30332-2000, United States.
Joseph KapciaDepartment of Molecular Biology and Biochemistry, University of California, Irvine, 3205 McGaugh Hall, Irvine, California 92697-2525, United States.
Neha GargSchool of Chemistry and Biochemistry, Georgia Institute of Technology, 950 Atlantic Drive, Atlanta, Georgia 30332-2000, United States.ORCID 0000-0002-2760-7123
Georgia Institute of Technology · USUniversity of California, Irvine · US

Funding

Molecular analysis of bacterial interactionsR35GM150870 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI Neha Garg · 2023 to 2026
$1.5M
NIGMS NIH HHS R35 GM150870
6 · The paper itself

Abstract

Opportunistic infections by

Indexed as

Biological ProductsTrimethoprimAnti-Bacterial AgentsHomogentisic AcidMetabolomicsAnti-Bacterial AgentsBiological ProductsHomogentisic AcidTrimethoprim

Identifiers

PMID36215670
PMCPMC13589308
OpenAlexW4304099386

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.