Evidence map›Paper›PMID 36215571›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2023

PET Imaging of Fibroblast Activation Protein in Various Types of Cancer Using

Yizhen Pang, Liang Zhao, Tinghua Meng, Weizhi Xu, Qin Lin, Hua Wu, Jingjing Zhang, Xiaoyuan Chen, Long Sun, Haojun Chen

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 3 pooled it
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 3 syntheses or guidelines pooled it, 101 citations in OpenAlex.

  1. Diagnostic Performance of Radiolabelled FAPI Versus [International journal of molecular sciences · 2025
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  4. Feasibility and therapeutic potential of [European journal of nuclear medicine and molecular imaging · 2024
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  5. Spatiotemporal voxel-wise concordance betweenEuropean journal of nuclear medicine and molecular imaging · 2026
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  9. Head-to-head comparison ofEuropean journal of nuclear medicine and molecular imaging · 2026
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  10. Comparative evaluation of [European journal of nuclear medicine and molecular imaging · 2026
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  11. Differential [European journal of nuclear medicine and molecular imaging · 2026
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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Yizhen PangDepartment of Nuclear Medicine and Minnan PET Center, First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Liang ZhaoDepartment of Nuclear Medicine and Minnan PET Center, First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Tinghua MengDepartment of Nuclear Medicine and Minnan PET Center, First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Weizhi XuDepartment of Nuclear Medicine and Minnan PET Center, First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Qin LinDepartment of Radiation Oncology, First Affiliated Hospital of Xiamen University, Xiamen, China.
Hua WuDepartment of Nuclear Medicine and Minnan PET Center, First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Jingjing ZhangDepartment of Diagnostic Radiology, National University of Singapore, Singapore.
Xiaoyuan ChenClinical Imaging Research Centre, Centre for Translational Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; leochen0821@foxmail.com 13178352662@163.com chen.shawn@nus.edu.sg.
Long SunDepartment of Nuclear Medicine and Minnan PET Center, First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China; leochen0821@foxmail.com 13178352662@163.com chen.shawn@nus.edu.sg.
Haojun ChenDepartment of Nuclear Medicine and Minnan PET Center, First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China; leochen0821@foxmail.com 13178352662@163.com chen.shawn@nus.edu.sg.
First Affiliated Hospital of Xiamen University · CNNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PET imaging that targets fibroblast activation protein (FAP) on the surface of cancer-associated fibroblasts has yielded promising tumor diagnostic results. FAP-2286 contains cyclic peptides as FAP-binding motifs to optimize tumor retention compared with the small-molecule FAP inhibitor (FAPI) series (FAPI-04/46). The aim of this study was to evaluate the diagnostic accuracy of

Indexed as

Cancer-Associated FibroblastsLiver NeoplasmsQuinolinesFluorodeoxyglucose F18Gallium RadioisotopesHumansPositron-Emission TomographyPositron Emission Tomography Computed TomographyProspective StudiesFAPI-46Fluorodeoxyglucose F18Gallium RadioisotopesQuinolinesFAP-2286FAPI-46fibroblast activation proteinPET/CT

Identifiers

PMID36215571
PMCPMC10071807
OpenAlexW4294276864

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.