Evidence map›Paper›PMID 36215042›Full record

ArticleNucleic acids research2023

MiMeDB: the Human Microbial Metabolome Database.

David S Wishart, Eponine Oler, Harrison Peters, AnChi Guo, Sagan Girod, Scott Han, Sukanta Saha, Vicki W Lui, Marcia LeVatte, Vasuk Gautam and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
8.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 101 citations in OpenAlex.

  1. Testosterone administration partially modulates gut microbiota responses to severe energy deficit.American journal of physiology. Endocrinology and metabolism · 2026
    Trial
  2. Gut microbes · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Recent Trends in Metabolomics by NMR Spectroscopy.Angewandte Chemie (International ed. in English) · 2026
    Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

David S WishartDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.ORCID 0000-0002-3207-2434
Eponine OlerDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Harrison PetersDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
AnChi GuoDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Sagan GirodDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.ORCID 0000-0002-8667-0907
Scott HanDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Sukanta SahaDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Vicki W LuiDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Marcia LeVatteDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Vasuk GautamDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Rima Kaddurah-DaoukDepartment of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.ORCID 0000-0003-1858-5732
Naama KaruLeiden Academic Centre for Drug Research, Leiden University, Leiden 2333 CC, The Netherlands.
University of Alberta · CADuke University · USLeiden University · NL

Funding

Project 4 - Mechanistic studies on the role of the gut microbiome in models for Alzheimer's diseaseU19AG063744 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ROB KNIGHT, Rima F Kaddurah-Daouk · 2019 to 2026
$54.1M
NIA NIH HHS U19 AG063744
6 · The paper itself

Abstract

The Human Microbial Metabolome Database (MiMeDB) (https://mimedb.org) is a comprehensive, multi-omic, microbiome resource that connects: (i) microbes to microbial genomes; (ii) microbial genomes to microbial metabolites; (iii) microbial metabolites to the human exposome and (iv) all of these 'omes' to human health. MiMeDB was established to consolidate the growing body of data connecting the human microbiome and the chemicals it produces to both health and disease. MiMeDB contains detailed taxonomic, microbiological and body-site location data on most known human microbes (bacteria and fungi). This microbial data is linked to extensive genomic and proteomic sequence data that is closely coupled to colourful interactive chromosomal maps. The database also houses detailed information about all the known metabolites generated by these microbes, their structural, chemical and spectral properties, the reactions and enzymes responsible for these metabolites and the primary exposome sources (food, drug, cosmetic, pollutant, etc.) that ultimately lead to the observed microbial metabolites in humans. Additional, extensively referenced data about the known or presumptive health effects, measured biosample concentrations and human protein targets for these compounds is provided. All of this information is housed in richly annotated, highly interactive, visually pleasing database that has been designed to be easy to search, easy to browse and easy to navigate. Currently MiMeDB contains data on 626 health effects or bioactivities, 1904 microbes, 3112 references, 22 054 reactions, 24 254 metabolites or exposure chemicals, 648 861 MS and NMR spectra, 6.4 million genes and 7.6 billion DNA bases. We believe that MiMeDB represents the kind of integrated, multi-omic or systems biology database that is needed to enable comprehensive multi-omic integration.

Indexed as

MetabolomicsProteomicsDatabases, FactualData ManagementHumansMetabolome

Identifiers

PMID36215042
PMCPMC9825614
OpenAlexW4304117487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.