Evidence map›Paper›PMID 36214895›Full record

SynthesisEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2023

Radiofrequency ablation is as safe and effective as surgical excision for spinal osteoid osteoma: a systematic review and meta-analysis.

Alessandro Sangiorgio, Lorenzo Massimo Oldrini, Christian Candrian, Costantino Errani, Giuseppe Filardo

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. What's new in pediatric bone sarcomas and benign bone tumors.Journal of children's orthopaedics · 2026
    Article
  3. Unusual Presentation of Spinal Osteoid Osteoma: A Case Report.Journal of orthopaedic case reports · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
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  12. Letter to the Editor concerning "Radiofrequency ablation is as safe and effective as surgical excision for spinal osteoid osteoma: a systematic review and meta-analysis" by Sangiorgio A, et al. [Eur Spine J (2023): doi:10.1007/s00586-022-07411-8].European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Alessandro SangiorgioService of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland. Alessandro.Sangiorgio@eoc.ch.ORCID 0000-0001-9550-5412
Lorenzo Massimo OldriniService of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland.ORCID 0000-0003-4302-6246
Christian CandrianService of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland.ORCID 0000-0002-3543-981X
Costantino ErraniClinica Ortopedica e Traumatologica III, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.ORCID 0000-0002-4504-2867
Giuseppe FilardoService of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland.ORCID 0000-0002-8136-0977
Istituto Ortopedico Rizzoli · ITOspedale regionale di Lugano · CHUniversità della Svizzera italiana · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteoid osteoma (OO) is a primary benign tumor that affects mainly young patients. Ten percent of all OO are located in the vertebral column. Treatment of spinal OO is challenging and there is no consensus in the literature on the best operative approach. PURPOSE: The aim of this systematic review and meta-analysis was to determine safety and efficacy of radiofrequency ablation (RFA) versus surgical excision for the treatment of spinal OO.

methodsA literature search was performed on PubMed, Web of Science, and Embase from inception up to 22 March 2022. Studies addressing surgical excision or RFA for the treatment of spinal OO were included. The main outcomes evaluated were pain before and after intervention, the treatments success rate, defined as complete pain relief with no recurrence until the last follow-up, and the number and type of complications.

resultsThirty-one studies (749 patients) were included. For patients who underwent surgical excision, 19 studies reported a mean treatment success rate of 85.6%, while in the RFA treatment group, 18 studies reported a mean success rate of 88.6%. At last follow-up, the pooled mean difference in pain scores from baseline on a 0-10 scale was 5.8 points in the surgical excision group and 6.7 points in the RFA group. Recurrences were observed in 5.6% of the patients who underwent surgical excision and in 6.7% of the patients treated with RFA. The complication rate was 7.8% in the surgical excision group and 4.4% in the RFA group.

conclusionsThis meta-analysis found high global success rates for both surgical and RFA treatments. Both treatments were efficient in pain relief and presented a low rate of recurrences. The complication rate was low for both treatments. Compared to surgical excision, RFA is a less invasive procedure which proved to be a safe and as effective option for the treatment of spinal OO.

Indexed as

Bone NeoplasmsCatheter AblationOsteoma, OsteoidRadiofrequency AblationSpinal NeoplasmsHumansPainSpineTreatment OutcomeOsteoid osteomaRFASpineSurgical excision

Identifiers

PMID36214895
OpenAlexW4304098009

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.