SynthesisAmerican journal of respiratory and critical care medicine2023
Mendelian Randomization Analysis Reveals a Complex Genetic Interplay among Atopic Dermatitis, Asthma, and Gastroesophageal Reflux Disease.
Open access · greenAbstract readMeta-Analysis
In one paragraph
Synthesis in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
11.3field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- The relationship between amino acids and gastroesophageal reflux disease: evidence from a mendelian randomization analysis combined with a meta-analysis.Frontiers in immunology · 2025Pooled it
- Unravelling the Links Between Gastroesophageal Reflux and Lung Disease: New Insights.Digestive diseases and sciences · 2026Review
- Genetic Correlations and Causal Relationships Among Allergic Diseases: A Comprehensive Mendelian Randomization Study With Multiomic Mediation Analysis.Mediators of inflammation · 2026Article
- Immune and environmental predictors of disease severity in atopic dermatitis: a retrospective cohort study.American journal of translational research · 2026Article
- The Relationship Between Immune Cells and Uterine Fibroids: A Bidirectional Mendelian Randomization Study.International journal of women's health · 2026Article
- Review
- Skin-lung axis in the atopic march: The immune link from skin to lungs.Chinese medical journal pulmonary and critical care medicine · 2025Review
- Identification of Proteomic Biomarkers and Therapeutic Targets for Vitiligo Using a Two-Sample Proteome-Wide Mendelian Randomization Approach.Journal of cosmetic dermatology · 2025Article
- Decoding Cuproptosis-Sphingolipid-Immune Crosstalk in Atopic Dermatitis: A Multi-Omics Network Analysis.Biomedicines · 2025Article
- Eosinophilic esophagitis and allergic susceptibility: A systematic review and meta-analysis.The World Allergy Organization journal · 2025Article
- Physical Exercise as a Therapeutic Approach in Gastrointestinal Diseases.Journal of clinical medicine · 2025Review
- Causal association of allergic diseases, eosinophils, and osteoporosis: A Mendelian randomization study.The World Allergy Organization journal · 2025Article
- Exploring the shared genetic mechanisms of atopic dermatitis and alopecia areata via bioinformatics approaches.Archives of dermatological research · 2025Article
- Association Between Gastroesophageal Reflux Disease, Barrett's Esophagus and Ear Disorders: A Mendelian Randomization Study.Journal of multidisciplinary healthcare · 2025Article
- The role of ILC2s in asthma combined with atopic dermatitis: bridging the gap from research to clinical practice.Frontiers in immunology · 2025Review
- An atlas of the shared genetic architecture between atopic and gastrointestinal diseases.Communications biology · 2024Article
- Shared genetic architecture between gastro-esophageal reflux disease, asthma, and allergic diseases.Communications biology · 2024Article
- Causal relationships between dietary antioxidant vitamin intake and atopic dermatitis: A two-sample Mendelian randomization study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Article
- Association between lipid-lowering drugs and allergic diseases: A Mendelian randomization study.The World Allergy Organization journal · 2024Article
- Higher risk of osteoporosis in adult-onset asthma than childhood-onset asthma: from genetic and prospective evidence.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024Article
Corrections and comments
- Commented on by
Authors and funding
6 authors at 5 institutions in 1 country.
Kwangmi AhnNeurobehavioral Clinical Research Section, Social and Behavioral Research Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland.
Raymond B PennDivision of Pulmonary and Critical Care Medicine and.
Satish RattanDivision of Gastroenterology & Hepatology, Department of Medicine, Center for Translational Medicine, Jane and Leonard Korman Respiratory Institute, Thomas Jefferson University, Philadelphia, Pennsylvania.
Reynold A PanettieriRutgers Institute for Translational Medicine and Science, New Brunswick, New Jersey.
Benjamin F VoightDepartment of Systems Pharmacology and Translational Therapeutics and.
Steven S AnRutgers Institute for Translational Medicine and Science, New Brunswick, New Jersey.ORCID 0000-0003-4723-1888
Rutgers, The State University of New Jersey · USNational Human Genome Research Institute · USPulmonary and Critical Care Associates · USThomas Jefferson University · USUniversity of Pennsylvania · US
Funding
Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI BRIAN T BUCKLEY · 1988 to 2026
$47.4MNew Jersey Alliance for Clinical Translational Science: NJ ACTSUL1TR003017 · NCATS · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI PANETTIERI, REYNOLD ALEXANDER · 2019 to 2023
$28.9MProject 4 - OGR1- and TSPO- dependent mechanisms mediated by benzodiazepines affecting ASM contractionP01HL114471 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI LIGGETT, STEPHEN B · 2013 to 2023
$23.9MG Protein-Coupled Receptor Signaling in Airway Smooth MuR01HL058506 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI RAYMOND B. PENN · 2001 to 2026
$9.3MNEUROHUMORAL CONTROL OF INTERNAL ANAL SPINCHTERR01DK035385 · NIDDK · THOMAS JEFFERSON UNIVERSITY · PI RATTAN, SATISH · 1986 to 2020
$7.8MNCATS NIH HHS UL1 TR003017NCATS NIH HHS UL1TR003017NHLBI NIH HHS P01 HL114471NHLBI NIH HHS P01HL114471NHLBI NIH HHS R01 HL058506NHLBI NIH HHS R01HL058506NIDDK NIH HHS R01 DK035385NIDDK NIH HHS R01DK035385NIEHS NIH HHS P30 ES005022
Abstract
PubMed holds no abstract for this paper.
Indexed as
AsthmaDermatitis, AtopicGastroesophageal RefluxGenome-Wide Association StudyHumansMendelian Randomization AnalysisPolymorphism, Single Nucleotidecausal pathwaysepidemiological approachhuman geneticsrisk factors
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.