Evidence map›Paper›PMID 36214677›Full record

ArticleMicrobiology spectrum2022

Isolation of an Extensively Drug-Resistant Pseudomonas aeruginosa

Andrés Opazo-Capurro, Felipe Morales-León, Christian Jerez, Jorge Olivares-Pacheco, Manuel Alcalde-Rico, Paulina González-Muñoz, Helia Bello-Toledo, Adriana Cardenas-Arias, Fernanda Esposito, Nilton Lincopán and 2 more

Open access · goldAbstract readLetter
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Andrés Opazo-CapurroLaboratorio de Antibióticos, Departamento de Microbiología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile.ORCID 0000-0002-6382-7625
Felipe Morales-LeónLaboratorio de Antibióticos, Departamento de Microbiología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile.
Christian JerezLaboratorio de Antibióticos, Departamento de Microbiología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile.
Jorge Olivares-PachecoMillennium Nucleus for Collaborative Research on Bacterial Resistance, Santiago, Chile.
Manuel Alcalde-RicoMillennium Nucleus for Collaborative Research on Bacterial Resistance, Santiago, Chile.
Paulina González-MuñozLaboratorio de Antibióticos, Departamento de Microbiología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile.
Helia Bello-ToledoLaboratorio de Antibióticos, Departamento de Microbiología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile.ORCID 0000-0002-9277-4681
Adriana Cardenas-AriasDepartment of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Fernanda EspositoDepartment of Clinical Analysis, School of Pharmacy, University of São Paulo, São Paulo, Brazil.
Nilton LincopánDepartment of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.ORCID 0000-0003-0161-5800
Vijna IllescaHospital Hernán Henríquez Aravena, Clinical Laboratory, Temuco, Chile.
Gerardo González-RochaLaboratorio de Antibióticos, Departamento de Microbiología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile.ORCID 0000-0003-2351-1236
University of Concepción · CLUniversidade de São Paulo · BRPontificia Universidad Católica de Valparaíso · CLHospital Doctor Hernán Henríquez Aravena · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the genomic features of an extensively drug-resistant (XDR) Pseudomonas aeruginosa isolate (P-469) emerging in Chile. Antibiotic susceptibility was determined by disk diffusion and "colistin agar" test. Whole-genome sequencing (WGS) was performed by the Illumina NextSeq 2000 platform, and epidemiologically and clinically relevant data (i.e., sequence-type, serotype, mobile genetic elements, virulome, resistome, plasmidome, prophages, and CRISPR-Cas systems) were retrieved using multiple bioinformatic tools. The P-469 strain displayed an XDR profile, remaining susceptible to colistin. Genomic analysis revealed that this isolate belonged to the "high-risk" clone ST654 (CC654), serotype O4, and genotype

Indexed as

Pseudomonas aeruginosaPseudomonas InfectionsAgarAnti-Bacterial Agentsbeta-LactamasesClone CellsColistinHumansMicrobial Sensitivity TestsAgarAnti-Bacterial Agentsbeta-lactamase NDM-1beta-LactamasesColistincarbapenem-resistant Pseudomonas aeruginosahigh-risk cloneNDM-1ST654VIM-80

Identifiers

PMID36214677
PMCPMC9604125
OpenAlexW4304118591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.