ArticleClinical implant dentistry and related research2023
Bone vitality and vascularization of mandibular and maxillary bone grafts in maxillary sinus floor elevation: A retrospective cohort study.
Article in Clinical implant dentistry and related research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- The effect of autologous platelet concentrates as solely grafting material or with bone graft materials in maxillary sinus augmentation: a meta-analysis of randomized controlled trials.Clinical oral investigations · 2025Pooled it
- Long-term effects of a bony mucoperiosteal flap on bone preservation in bony impacted upper third molar surgery: a prospective exploratory study.BMC oral health · 2026Article
- Jaw-specific differential kinase activity profiles in human periodontal ligament stem cells under mechanical compression.Stem cell research & therapy · 2025Article
- Long-Term Bone Height Changes After Sinus Floor Elevation With Maxillary or Mandibular Bone Grafts: A Radiological Study.Clinical implant dentistry and related research · 2025Article
- Trabecular Bone Component Assessment under Orthodontic Loads and Movements during Periodontal Breakdown-A Finite Elements Analysis.Dentistry journal · 2024Article
- Effects of Increasing the Orthodontic Forces over Cortical and Trabecular Bone during Periodontal Breakdown-A Finite Elements Analysis.Medicina (Kaunas, Lithuania) · 2023Article
- Cortical and Trabecular Bone Stress Assessment during Periodontal Breakdown-A Comparative Finite Element Analysis of Multiple Failure Criteria.Medicina (Kaunas, Lithuania) · 2023Article
- Bone vitality and vascularization of mandibular and maxillary bone grafts in maxillary sinus floor elevation: A retrospective cohort study.Clinical implant dentistry and related research · 2023Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesMandibular retromolar (predominantly cortical) and maxillary tuberosity (predominantly cancellous) bone grafts are used in patients undergoing maxillary sinus floor elevation (MSFE) for dental implant placement. The aim of this retrospective cohort study was to investigate whether differences exist in bone formation and vascularization after grafting with either bone source in patients undergoing MSFE.
methodsFifteen patients undergoing MSFE were treated with retromolar (n = 9) or tuberosity (n = 6) bone grafts. Biopsies were taken 4 months postoperatively prior to dental implant placement, and histomorphometrically analyzed to quantify bone and osteoid area, number of total, apoptotic, and receptor activator of nuclear factor-κB ligand (RANKL)-positive osteocytes, small and large-sized blood vessels, and osteoclasts. The grafted area was divided in three regions (caudal-cranial): RI, RII, and RIII.
resultsBone volume was 40% (RII, RIII) higher and osteoid volume 10% (RII) lower in retromolar compared to tuberosity-grafted areas. Total osteocyte number and number of RANKL-positive osteocytes were 23% (RII) and 90% (RI, RII) lower, but osteoclast number was higher (retromolar: 12, tuberosity: 0) in retromolar-grafted areas. The total number of blood vessels was 80% (RI) to 60% (RIII) lower, while the percentage of large-sized blood vessels was 86% (RI) to 25% (RIII) higher in retromolar-grafted areas. Number of osteocyte lacunae and apoptotic osteocytes were similar in both bone grafts used.
conclusionsCompared to the retromolar bone, tuberosity bone showed increased bone vitality and vascularization in patients undergoing MSFE, likely due to faster bone remodeling or earlier start of new bone formation. Therefore, tuberosity bone grafts might perform better in enhancing bone regeneration.
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