ArticleEpidemiology and psychiatric sciences2022
Adherence to dietary guidelines and risk of dementia: a prospective cohort study of 94 184 individuals.
Article in Epidemiology and psychiatric sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Associations between self-reported change in lifestyle behaviors and brain health: Findings from the Healthy Brain Initiative.Journal of Alzheimer's disease : JAD · 2026Article
- Dietary habits, nutritional supplement use, and adherence to national dietary guidelines in patients with psoriasis.Scientific reports · 2025Article
- Causal cardiovascular risk factors for dementia: insights from observational and genetic studies.Cardiovascular research · 2025Review
- Shared Risk Factors between Dementia and Atherosclerotic Cardiovascular Disease.International journal of molecular sciences · 2022Review
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Authors and funding
6 authors.
Funding
Abstract
aimsRecent estimates suggest that 40% of dementia cases could be avoided by treating recognised cardiovascular risk factors such as hypertension, diabetes, smoking and physical inactivity. Whether diet is associated with dementia remains largely unknown. We tested if low adherence to established dietary guidelines is associated with elevated lipids and lipoproteins and with increased risk of Alzheimer's disease and non-Alzheimer's dementia – a dementia subtype with a high frequency of cardiovascular risk factors.
methodsWe used the prospective Copenhagen General Population Study including 94 184 individuals with dietary information and free of dementia at baseline. Mean age at study entry was 58 years, and 55% (
resultsLow-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol and plasma triglyceride levels were higher in individuals with intermediate and low adherence to dietary guidelines compared with individuals with high adherence (all
conclusionsLow adherence to national dietary guidelines is associated with an atherogenic lipid profile and with increased risk of non-Alzheimer's dementia – the subtype of dementia with a high frequency of vascular risk factors. This study suggests that implementation of dietary guidelines associated with an anti-atherogenic lipid profile could be important for prevention of non-Alzheimer's dementia.
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