Evidence map›Paper›PMID 36213745›Full record

ArticleFrontiers in neuroscience2022

Resting-state brain network in Parkinson's disease with different degrees of depression.

Qinru Liu, Zhenni Mao, Changlian Tan, Sainan Cai, Qin Shen, Min Wang, Junli Li, Lin Zhang, Fan Zhou, Chendie Song and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Qinru LiuDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Zhenni MaoDepartment of Radiology, The Third Hospital of Changsha, Changsha, China.
Changlian TanDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Sainan CaiDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Qin ShenDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Min WangDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Junli LiDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Lin ZhangDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Fan ZhouDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Chendie SongDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Jiaying YuanDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Yujing LiuDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Jun LiuDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Haiyan LiaoDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Second Xiangya Hospital of Central South University · CNCentral South University · CNThird Hospital of Changsha · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of this study is to explore the neural network mechanism of Parkinson's disease (PD) with different degrees of depression using independent component analysis (ICA) of the functional connectivity changes in the forehead, limbic system, and basal ganglia regions. Methods: A total of 106 patients with PD were divided into three groups: PD with moderate-severe depression (PDMSD, Results: Different functional connectivity was observed in the left precentral gyrus, right precuneus, right inferior frontal gyrus, right medial and paracingulate gyrus, left supplementary motor area, right brain insula, and the inferior frontal gyrus of the left orbit among the four groups (ANOVA, Conclusion: PD with different degrees of depression has abnormal functional connectivity in multiple networks, which is an important neurobiological basis for the occurrence and development of depression in PD. The degree of decreased functional connectivity in the inSN network is related to the degree of depression in patients with PD-D, which can be an imaging marker for PD to judge the severity of depression.

Indexed as

depressionfunctional connectivityindependent component analysisParkinson’s diseaseresting-state functional magnetic resonance imaging

Identifiers

PMID36213745
PMCPMC9533063
OpenAlexW4296743004

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.