Evidence map›Paper›PMID 36213597›Full record

ArticlePain reports

Fibromyalgia in women: association of inflammatory plasma proteins, muscle blood flow, and metabolism with body mass index and pain characteristics.

Bijar Ghafouri, Emelie Edman, Marie Löf, Eva Lund, Olof Dahlqvist Leinhard, Peter Lundberg, Mikael Fredrik Forsgren, Björn Gerdle, Huan-Ji Dong

Open access · goldAbstract read
In one paragraph

Article in Pain reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Bijar GhafouriDepartment of Health, Medicine, and Caring Sciences, Pain and Rehabilitation Centre, Linköping University, Linköping, University Sweden.ORCID https://orcid.org/0000-0002-6396-5104
Emelie EdmanDepartment of Health, Medicine, and Caring Sciences, Pain and Rehabilitation Centre, Linköping University, Linköping, University Sweden.
Marie LöfDepartment of Health, Medicine, and Caring Sciences, Linköping University, Linköping, Sweden.
Eva LundDepartment of Radiation Physics, and Department of Health, Medicine, and Caring Sciences, Linköping University, Linköping, Sweden.
Olof Dahlqvist LeinhardDepartment of Radiation Physics, and Department of Health, Medicine, and Caring Sciences, Linköping University, Linköping, Sweden.
Peter LundbergDepartment of Radiation Physics, and Department of Health, Medicine, and Caring Sciences, Linköping University, Linköping, Sweden.
Mikael Fredrik ForsgrenDepartment of Radiation Physics, and Department of Health, Medicine, and Caring Sciences, Linköping University, Linköping, Sweden.
Björn GerdleDepartment of Health, Medicine, and Caring Sciences, Pain and Rehabilitation Centre, Linköping University, Linköping, University Sweden.
Huan-Ji DongDepartment of Health, Medicine, and Caring Sciences, Pain and Rehabilitation Centre, Linköping University, Linköping, University Sweden.
Linköping University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Obesity is a common comorbidity in fibromyalgia (FM). Both FM and obesity have been connected to low-grade inflammation, although it is possible that previously reported inflammatory alterations in FM primarily may be linked to increased body mass index (BMI). Objective: This study aimed to investigate whether the inflammatory plasma protein profile, muscle blood flow, and metabolism and pain characteristics (clinical parameters and patient-reported outcome measurements) differed between female patients with FM with and without obesity. Methods: Patients with FM underwent clinical examinations, physical tests, and answered questionnaires. They were dichotomized according to BMI (<30 kg/m Results: There were significant ( Conclusions: These findings suggest that metabolism and inflammation interact in female patients with FM with obesity and might cause chronic low-grade inflammation. Screening for obesity and monitoring of BMI changes should be considered in the treatment of patients with FM.

Identifiers

PMID36213597
PMCPMC9534367
OpenAlexW4302307423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.