Evidence map›Paper›PMID 36213578›Full record

SynthesisComputational and mathematical methods in medicine2022

Meta-Analysis on the Anesthetic Effects of Remifentanil plus Dexmedetomidine versus Remifentanil Alone in Cardiac Surgery.

Xiao-Lin Zeng, Jun-Hua Liao, Hui-Sheng Zhong, Xin-Hua Yin, Rui Wang, Jiu-Ping Liang, Zheng-Sheng Zhang

Retracted Registry-linked trialOpen access · hybridAbstract readMeta-AnalysisRetracted Publication
In one paragraph

Synthesis in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. It is linked to trial NCT07695220 (Efficacy and Safety of an Early Intensive Blood Pressure-Lowering Strategy Using Remifentanil and Dexmedetomidine in Patients With Spontaneous Intracerebral Hemorrhage), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07695220 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Efficacy and Safety of an Early Intensive Blood Pressure-Lowering Strategy Using Remifentanil and Dexmedetomidine in Patients With Spontaneous Intracerebral Hemorrhage: A Multicenter, Prospective, Superiority, Randomized Controlled Trial

TypeinterventionalSponsorThe Third Affiliated Hospital of Southern Medical UniversityRan2026 to 2028Enrolled1,116ConditionsIntracerebral HemorrhageArmsRemifentanil and Dexmedetomidine, Guideline standard care
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Xiao-Lin ZengDepartment of Cardiology, Shenzhen University General Hospital, Shenzhen, China.ORCID https://orcid.org/0000-0001-6478-6477
Jun-Hua LiaoGuangzhou Yujia Biotechnology Co., Ltd., Guangzhou, China.
Hui-Sheng ZhongCardiac Surgery Center, The First Affiliated Hospital of Gannan Medical University, Jiangxi, China.
Xin-Hua YinDepartment of Cardiology, Shenzhen University General Hospital, Shenzhen, China.
Rui WangDepartment of Cardiology, Shenzhen University General Hospital, Shenzhen, China.
Jiu-Ping LiangDepartment of Radiology, Shenzhen Bao'an District Songgang People's Hospital, Shenzhen, China.
Zheng-Sheng ZhangDepartment of Cardiology, Pingshan District People's Hospital of Shenzhen, Pingshan General Hospital of Southern Medical University, Shenzhen, Guangdong, China.ORCID https://orcid.org/0000-0002-7637-096X
Shenzhen University · CNFirst Affiliated Hospital of Gannan Medical University · CNShenzhen Bao'an District People's Hospital · CNSouthern Medical University Shenzhen Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we performed a meta-analysis to investigate the anesthesia effects of remifentanil plus dexmedetomidine versus remifentanil alone in cardiac surgery. Literature search was performed on PubMed, Web of Science, Embase, China Knowledge Infrastructure, Wanfang Data, and other databases for relevant literature published in English or Chinese before October 2021. A total of 17 studies, consisting of 1350 patients, were included in this study. Of these, 10 studies showed that remifentanil plus dexmedetomidine had a good anesthesia effect in cardiac surgery (OR = 3.61, 95% CI: 1.73, 7.52,

Indexed as

AnestheticsCardiac Surgical ProceduresDexmedetomidineHumansPiperidinesRemifentanilAnestheticsDexmedetomidinePiperidinesRemifentanil

Identifiers

PMID36213578
PMCPMC9534643
OpenAlexW4297521019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.